基本信息
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Career Trajectory
Bio
He has published over 390 papers and his work has been recognised with several awards including the RSC Hickinbottom Fellowship and Corday Morgan Medal (both in 1986), the Tilden Medal and Lectureship (2000-2001), the Adrien Albert Medal and Lectureship (2001), an EPSRC Senior Research Fellowship (2000-2005), the Royal Society of Chemistry Award for Synthetic Organic Chemistry (2006), the Pedler Lectureship (2008), the Novartis International Lectureship (2010-2011), and the Royal Society of Chemistry Charles Rees Award (2012).
Research Summary
Sustainable synthetic methodology
new methods in heterocyclic chemistry; new routes to indoles, pyridines, oxazoles, thiazoles etc.
dirhodium(II) catalysed N-H insertion reaction
precious metal free coupling reactions
solar photochemistry
catalytic oxidation methods in organic synthesis
Natural Product Synthesis
marine natural products
cyclic peptides
thiopeptide antibiotics
quinone ansamycin antibiotics
Molecular targeting of cancer, malaria and neurodegeneration
anticancer agents based on heterocyclic quinones
design of substrates and inhibitors of NADH quinone oxidoreductase (NQO1, NQO2)
role of other redox enzymes in disease, e.g. thioredoxin, indoleamine dioxygenase (IDO)
inhibitors of heat shock proteins.
Research Summary
Sustainable synthetic methodology
new methods in heterocyclic chemistry; new routes to indoles, pyridines, oxazoles, thiazoles etc.
dirhodium(II) catalysed N-H insertion reaction
precious metal free coupling reactions
solar photochemistry
catalytic oxidation methods in organic synthesis
Natural Product Synthesis
marine natural products
cyclic peptides
thiopeptide antibiotics
quinone ansamycin antibiotics
Molecular targeting of cancer, malaria and neurodegeneration
anticancer agents based on heterocyclic quinones
design of substrates and inhibitors of NADH quinone oxidoreductase (NQO1, NQO2)
role of other redox enzymes in disease, e.g. thioredoxin, indoleamine dioxygenase (IDO)
inhibitors of heat shock proteins.
Research Interests
Papers共 355 篇Author StatisticsCo-AuthorSimilar Experts
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European Journal of Medicinal Chemistry (2023): 115507-115507
Steven M Wales, Elena G Merisor,Holly V Adcock,Christopher A Pearce, Ian R Strutt,William Lewis,Daniel Hamza,Christopher J Moody
RSC ADVANCESno. 77 (2017): 49056-49056
RSC ADVANCESno. 75 (2017): 47297-47308
ChemInformno. 7 (2016)
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