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致力于基于我国特色天然产物的创新药物发现及相关基础研究。通过天然产物全合成及其结构优化、化学蛋白质组学、生物信息学和分子影像等多学科手段,系统构建了基于天然产物的药物化学生物学研究体系,揭示多个天然产物作用靶标与机制,获得抗急性肺损伤和肿瘤免疫治疗等多个原创性药物候选化合物。2个1类候选新药处于临床前研究,其中,基于肿瘤免疫治疗的1类候选新药已实现成果转让。主持国家基金委青年、面上项目、中科院先导专项子课题及上海市科委等5项科研项目。发表第一/通讯作者SCI论文28篇,包括Chem Sci, J Med Chem, Cancer Res,Anal Chem, Org Lett, Cancer Lett和ChemComm等JCR 1区期刊18篇。入选上海市浦江人才计划,获赛诺菲-上海生科院优秀青年人才奖和中国精准医疗大会-青年学者创新成果展示。
Research Interests
Papers共 129 篇Author StatisticsCo-AuthorSimilar Experts
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Ruoqing Zeng,Meimiao Fang,Ancheng Shen,Xiaolei Chai,Yumiao Zhao, Mingyao Liu, Lingfeng Zhu,Weiwei Rui,Bo Feng,Liang Hong,Chunyong Ding,Zilan Song,
Journal of medicinal chemistryno. 5 (2024): 3520-3541
Ruoqing Zeng,Meimiao Fang,Ancheng Shen,Xiaolei Chai,Yumiao Zhao, Mingyao Liu, Lingfeng Zhu, Weiwei Rui, Bo Feng, Liang Hong,Chunyong Ding,Zilan Song,
JOURNAL OF MEDICINAL CHEMISTRYno. 5 (2024): 3520-3541
Journal of medicinal chemistryno. 22 (2023): 15524-15549
Yihua Lin, Yiling Zhao,Minggui Chen, Zishuo Li,Qiao Liu,Jian Chen,Yi Ding,Chunyong Ding,Ye Ding,Cuiling Qi,Lingyun Zheng,Jiangchao Li,
Journal of Medicinal Chemistryno. 22 (2023): 15524-15549
Chemical scienceno. 22 (2023): 5956-5964
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Author Statistics
#Papers: 134
#Citation: 2663
H-Index: 29
G-Index: 47
Sociability: 6
Diversity: 0
Activity: 2
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