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个人简介
Our research focuses on how genotypes produce phenotypes and how they vary and evolve. We are particularly interested in identifying and experimentally characterizing functional human non-coding sequence variation. We aim to understand the mechanisms through which non-coding variants function, with an emphasis on understanding the mechanisms underlying complex human disease. We leverage a combination of high throughput experimental and computational approaches. We are currently focused on massively parallelizing assays that interrogate non-coding DNA function and applying these approaches to the fine-mapping of the causal variants underlying human disease.
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Bárbara Silva-Passadouro, Arnas Tamasauskas, Omar Khoja,Alexander J. Casson,Ioannis Delis,Christopher Brown,Manoj Sivan
Clinical Neurophysiology (2024): 209-222
biorxiv(2023)
Tyler Mari, Jessica Henderson,S. Hasan Ali, Danielle Hewitt,Christopher Brown, Andrej Stancak,Nicholas Fallon
biorxiv(2023)
Christopher Brown,Sandhitsu Das,Ilya Nasrallah,John Detre,Paul Yushkevich, Corey McMillan,David Wolk
NEUROLOGYno. 17 (2023)
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Communications biologyno. 1 (2023): 852-15
Danielle Hewitt, Adam Byrne,Jessica Henderson, Kathryn Wilford, Rajiv Chawla,Manohar Lal Sharma, Bernhard Frank,Nicholas Fallon,Christopher Brown,Andrej Stancak
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