Christopher J Hanley

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Bio

Christopher J Hanley currently works at the Academic Unit of Cancer Sciences, University of Southampton. Christopher does research in Cancer Research, Molecular Biology and Cell Biology. Their most recent publication is 'Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4'.

Research Interests

Papers共 50 篇Author StatisticsCo-AuthorSimilar Experts

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Single Cell and Spatial Analysis of Immune-Hot and Immune-Cold Tumours Identifies Fibroblast Subtypes Associated with Distinct Immunological Niches and Positive Immunotherapy Response

Benjamin H. Jenkins,Ian Tracy, Maria Fernanda S. D. Rodrigues, Melanie J. L. Smith, Begoña R. Martinez,Mark Edmond,Sangeetha Mahadevan, Anjali Rao, Hailing Zong, Kai Liu,Abhishek Aggarwal, Li,Lauri Diehl,Emma V. King,Jamie G. Bates,Christopher J. Hanley,Gareth J. Thomas

Molecular Cancerno. 1 (2025): 1-21

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Differentiation Signals Induce APOBEC3A Expression Via GRHL3 in Squamous Epithelia and Squamous Cell Carcinoma

Nicola J. Smith,Ian Reddin, Paige Policelli,Sunwoo Oh, Nur Zainal, Emma Howes, Benjamin Jenkins,Ian Tracy,Mark Edmond,Benjamin Sharpe, Damian Amendra,Ke Zheng,Nagayasu Egawa,John Doorbar, Anjali Rao,Sangeetha Mahadevan,Michael A. Carpenter,Reuben S. Harris,Simak Ali,Christopher Hanley,Remi Buisson,Emma King,Gareth J. Thomas,Tim R. Fenton

EMBO JOURNALno. 1 (2025): 1-29

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Differentiation Signals Via Grainyhead-like Transcription Factor 3 Induce Expression of the DNA Mutating Enzyme APOBEC3A in Healthy and Cancerous Epithelial Cells: Implications for Somatic Mutagenesis and Drug Resistance

N. J. Smith, I. G. Reddin, P. Policelli, N. S. B. Zainal, B. P. Sharpe, E. Howes, I Tracy, B. H. Jenkins, M. Edmond, E. King, N. Egawa,J. Doorbar, M. A. Carpenter, R. S. Harris, S. Ali,C. J. Hanley,G. J. Thomas, T. R. Fenton

JOURNAL OF PATHOLOGY (2024): S5-S5

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Differentiation Signals Induce APOBEC3A Expression Via GRHL3 in Squamous Epithelia and Squamous Cell Carcinoma

Nicola J Smith,Ian Reddin, Paige Policelli,Sunwoo Oh, Nur Zainal, Emma Howes, Benjamin Jenkins,Ian Tracy,Mark Edmond,Benjamin Sharpe, Damian Amendra,Ke Zheng,Nagayasu Egawa,John Doorbar, Anjali Rao,Sangeetha Mahadevan,Michael A Carpenter,Reuben S Harris,Simak Ali,Christopher Hanley,Rémi Buisson,Emma King,Gareth J Thomas,Tim R Fenton

Research square (2024)

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Developmental Programmes Drive Cellular Plasticity, Disease Progression and Therapy Resistance in Lung Adenocarcinoma

Kamila J Bienkowska, Stephany Gallardo, Nur Zainal,Matthew Ellis,Maria-Antoinette Lopez, Judith Austine, Sai Pittla,Serena J Chee,Aiman Alzetani,Emily C Shaw,Christian H Ottensmeier,Gareth J Thomas,Christopher J Hanley

biorxiv（2024）

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31P Crown-like Structures Are Associated with Changes in Immune Cell Infiltrates and Gene Signatures in Patients with Primary Invasive Breast Cancer

C. Savva, K. Boukas, C. Birts,M. Ashton-Key, K. Durkin,C.J. Hanley, M. Ellis, R.C.G. Smith,S. Thirdborough, P. Johnson,E. Copson,R. Cutress,S. Beers

ESMO Open (2024): 103039

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Video 1 from Tumor-Resident Stromal Cells Promote Breast Cancer Invasion Through Regulation of the Basal Phenotype

Christopher J. Hanley,Elodie Henriet,Orit Katarina Sirka,Gareth J. Thomas,Andrew J. Ewald

openalex（2023）

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Improved Understanding of NSCLC Immunotherapy Response Mechanisms from Single-Cell Analysis

Kamila Justyna Bienkowska,Christopher Jon Hanley

TRANSLATIONAL LUNG CANCER RESEARCHno. 8 (2023): 1807-1811

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Papers共 50 篇Author StatisticsCo-AuthorSimilar Experts