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We aim to understand the code for RNA splicing: how the precise locations of introns and splice sites are identified in primary transcripts and how its specificity changes in different cell types. Toward this end, we are mapping the RNA-binding affinity spectra of dozens of human RNA-binding proteins and integrating this information with in vivo binding and activity data. We are also studying the functions of 3’ untranslated regions, including their roles in mRNA localization and microRNA regulation. The lab uses a combination of computational and experimental approaches to address these questions.
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论文共 152 篇作者统计合作学者相似作者
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Connor J Kenny,Michael P McGurk, Sandra Schuler, Aidan Cordero, Sascha Laubinger,Christopher B Burge
biorxiv(2024)
Sarah E Harris, Maria S Alexis,Gilbert Giri, Francisco F Cavazos,Jernej Murn,Maria M Aleman,Christopher B Burge,Daniel Dominguez
bioRxiv : the preprint server for biology (2024)
AMERICAN JOURNAL OF HUMAN GENETICSno. 2 (2024): 350-363
Carlos G Vanoye,Tatiana V Abramova,Jean-Marc DeKeyser, Nora F Ghabra, Madeleine J Oudin,Christopher B Burge,Ingo Helbig,Christopher H Thompson,Alfred L George
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Alexandra C Martin-Geary,Alexander J M Blakes,Ruebena Dawes,Scott D Findlay,Jenny Lord,Susan Walker, Jonathan Talbot-Martin, Nechama Wieder,Elston N D'Souza,Maria Fernandes,Sarah Hilton,Nayana Lahiri,
medRxiv : the preprint server for health sciences (2023)
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Benjamin Boyerinas,Sun-Mi Park,Noam Shomron, Mads M. Hedegaard,Jeppe Vinther,Jens S. Andersen,Christine Feig,Jinbo Xu,Christopher B. Burge, Marcus E. Peter
crossref(2023)
crossref(2023)
Benjamin Boyerinas,Sun-Mi Park,Noam Shomron, Mads M. Hedegaard,Jeppe Vinther,Jens S. Andersen,Christine Feig,Jinbo Xu,Christopher B. Burge, Marcus E. Peter
crossref(2023)
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