基本信息
views: 9
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
The Hunter laboratory has several areas of research that center around understanding how the immune system deals with T. gondii. The first focuses on host pathogen interactions at the cellular level and how the parasite interacts with intracellular signaling pathways (NF-kB/JAK-STAT). In collaboration with the Roos laboratory, genetic approaches are being used to identify parasite factors that are involved in these events. This is part of work in progress which has used transgenic parasites to address fundamental questions about which cells are important in the initiation of adaptive immunity and the role of cross-presentation in the development of T cell responses. These latter studies compliment the work in the laboratory that has helped to define the cytokine networks that regulate the balance between protective and pathological immune responses and current studies focus on the IL-6 family of cytokines in these events. Lastly the laboratory is interested in better understanding the pathogenesis of toxoplasmic encephalitis (TE) in the immunocompromised patients who develop this disease. This work has also led the laboratory to try and apply what we have learned in TE to better understand the neuro-pathogenesis of African sleeping sickness.
Research Areas: Infectious Disease, Toxoplasma gondii, Zoonotic diseases, Host-pathogen interactions, Immunology, Parasites, Parasitology, Transgenic parasites, Inflammatory responses
Research Areas: Infectious Disease, Toxoplasma gondii, Zoonotic diseases, Host-pathogen interactions, Immunology, Parasites, Parasitology, Transgenic parasites, Inflammatory responses
Research Interests
Papers共 521 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
biorxiv(2024)
biorxiv(2024)
MBIOno. 3 (2024): e0008324-e0008324
The Journal of experimental medicineno. 7 (2024)
Ryan D Pardy,Katelyn A Walzer,Bethan A Wallbank,Jessica H Byerly,Keenan M O'Dea,Ian S Cohn,Breanne E Haskins,Justin L Roncaioli, Eleanor J Smith, Gracyn Y Buenconsejo,Boris Striepen,Christopher A Hunter
PLoS pathogensno. 5 (2024): e1011820-e1011820
Blood advancesno. 8 (2024): 2032-2043
Nature communicationsno. 1 (2024): 4350-4350
Emiley A Eloe-Fadrosh,Christopher J Mungall,Mark Andrew Miller,Montana Smith, Sujay Sanjeev Patil,Julia M Kelliher, Leah Y D Johnson, Francisca E Rodriguez,Patrick S G Chain,Bin Hu, Michael B Thornton,Lee Ann McCue,
Methods in molecular biology (Clifton, N.J.) (2024): 587-609
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn