基本信息
浏览量:37
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
After completing my studies in biochemistry, molecular and cell biology at the University Cote d'Azur (UCA), I did my PhD in the group of Pr Michel Lazdunski at the "Institut de Pharmacologie Moléculaire et Cellulaire" (IPMC), Valbonne, France (1999-2003). During my PhD, I cloned and functionally characterized new members of an emerging (at that time) family of potassium channel called the two-pore domain potassium channels family. Attracted by translational science, in 2004, I joined the group of Pr Frances Ashcroft as a post-doctoral fellow in the Department of Physiology, Anatomy and Genetics (DPAG), Oxford, UK. From 2004 to 2008, my research focused on the role played by ATP-sensitive potassium channels (KATP channels) in neonatal diabetes. Our group made fundamental discoveries that contributed to life-changing treatments for the patients. Back in France in 2009, I joined the lab headed by Dr Gerard Lambeau as a post-doctoral fellow. In 2010, I was appointed CNRS research scientist. From 2009 to 2013, I concentrated my research on the physiopathological roles of the phospholipase A2 receptor (PLA2R1). My work contributed to a better understanding of both PLA2R1 tumor-suppressive role in cancer and in the etiology of membranous nephropathy, the main cause of nephrotic syndrome. in 2014, I joined the group co-headed by Drs Sophie Tartare-Deckert and Marcel Deckert. Since then, my research focuses on the role exerted by tumor microenvironment in melanoma progression and resistance to therapies. I am particularly interested in identifying and characterizing new actors involved in the biomechanical dialog that takes place between the extracellular matrix (ECM) and tumor cells with the aim of identifying novel druggable targets.
研究兴趣
论文共 77 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
crossref(2023)
crossref(2023)
crossref(2023)
crossref(2023)
crossref(2023)
crossref(2023)
crossref(2023)
crossref(2023)
crossref(2023)
crossref(2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn