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The skeletal muscle is a highly plastic organ, able to adapt to contraction, nutrient availability and supply, ambient oxygen and temperature, as well as numerous other perturbations. In recent years, novel functions of muscle beyond force generation have been discovered, with enormous physiological and clinical implications.
We are interested in understanding and linking molecular mechanisms to physiological processes and pathophysiological events in skeletal muscle. In addition, the interaction of muscle with other cell types and tissues, e.g. the neuromuscular junction (NMJ) and motor neurons, is interrogated to reveal insights about the broader aspects of muscle plasticity. Therefore, we study exercise – the main physiological function of muscle – juxtaposed to inactivity, aging, cancer cachexia, muscular dystrophies and other muscle wasting pathologies.
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Papers共 199 篇Author StatisticsCo-AuthorSimilar Experts
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Ajda Lenardič,Seraina A Domenig,Joel Zvick,Nicola Bundschuh,Monika Tarnowska-Sengül,Regula Furrer, Falko J Noé, Christine Ling Li Trautmann,Adhideb Ghosh, Giada Bacchin, Pjeter Gjonlleshaj,Xhem Qabrati,
The Journal of clinical investigation (2024)
NATURE METABOLISM (2023)
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Regula Furrer, Barbara Heim, Svenia Schmid,Karl J.V. Nordström,Sedat Dilbaz,Danilo Ritz,Volkan Adak,Stefan A. Steurer,Jörn Walter,Christoph Handschin
bioRxiv (Cold Spring Harbor Laboratory)no. 11 (2023): 2020-2035
Physiological reportsno. 11 (2023): n/a-n/a
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