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Our approach is translational, bringing clinical hypothesis and samples into the laboratory, and using metagenomics and molecular microbiology for both “in patient” and “in vitro” studies. With this approach we characterized the development of resistance upon therapy and identified Quorum-Sensing (QS) as a major risk factor for the progression from colonization to P. aeruginosa infections.
Ongoing projects include:
Developing new antimicrobial biological dressings for burn patients in collaboration with a SwissTransMed network
Studying the dynamics of allograft colonization and the adaptation of P. aeruginosa to a new microenvironement after lung transplantation (Roche Organ Transplant Research Foundation)
Investigating in vitro bacterial interspecies competition and adaptation between P. aeruginosa and clinicaly relevant co-colonizing respiratory species (FNRS)
Searching to improve antimicrobial uptake using bacterial iron transport systems (Innovative Medicine Initiative, ND4BB)
研究兴趣
论文共 163 篇作者统计合作学者相似作者
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Clinical infectious diseases : an official publication of the Infectious Diseases Society of Americano. 2 (2024): 312-323
Mikael Tognon,Arnaud Riat, Chloé Cantero, Gregory Berra, Basile Landis,Christian van Delden,Jacques Schrenzel
SSRN Electronic Journal (2023)
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Transplant infectious disease : an official journal of the Transplantation Society (2023)
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Thilo Köhler,Alexandre Luscher, Léna Falconnet,Grégory Resch, Robert McBride, Quynh-Anh Mai,Juliette L. Simonin,Marc Chanson,Bohumil Maco,Raphaël Galiotto,Arnaud Riat, Natacha Civic,
Nature communicationsno. 1 (2023): 4443-4443
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