基本信息
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Bio
Professor Chris Lord is Deputy Head of Division, Team Leader of the CRUK Gene Function Laboratory and Professor of Cancer Genomics in the Breast Cancer Now Toby Robins Research Centre at The Institute of Cancer Research, London. Much of his work focuses on exploiting genetic concepts such as synthetic lethality to identify new approaches to treating cancer and to understand the variable effectiveness of existing treatments.
More recently, Chris has focused on using high-throughput genetic perturbation screens to understand the principles that govern the robustness of synthetic lethal interactions (e.g. Elife 2020). The impact of the work led by Lord is demonstrated by the multiple biomarkers of drug sensitivity/resistance and novel synthetic lethal approaches to the treatment of ARID1A, Rb or E-cadherin defective cancers now being assessed in clinical trials.
Research Interests
Papers共 581 篇Author StatisticsCo-AuthorSimilar Experts
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Maria Teresa Herrera Abreu, Uzma Khalid,Jian Ning,Rosalind Cutts, Gemma Wilson,Christopher Lord, Amanda Swain,Nicholas Turner
CANCER RESEARCHno. 9 (2024)
Annals of oncology : official journal of the European Society for Medical Oncologyno. 4 (2024): 364-380
MOLECULAR ONCOLOGYno. 2 (2024): 369-385
Maria Teresa Herrera Abreu, Uzma Khalid,Jian Ning,Rosalind Cutts, Gemma Wilson,Christopher Lord,Amanda Swain,Nicholas Turner
Cancer Researchno. 9_Supplement (2024): PS12-04
Elizabeth Harvey-Jones,Maya Raghunandan, Luisa Robbez-Masson,Thanussuyah Alaguthurai,Alba Llop-Guevara,Jennifer Trendell,Olga Rodriguez,Marta Guzman,Daniel Weekes, Christelle deRenty,Eleanor Knight,Rebecca Marlow,
Cancer Researchno. 9_Supplement (2024): RF01-05
bioRxiv : the preprint server for biology (2024)
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Author Statistics
#Papers: 582
#Citation: 41549
H-Index: 88
G-Index: 199
Sociability: 8
Diversity: 0
Activity: 5
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