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Bio
Chia-Yu Chen is a Postdoctoral Research Fellow at the Wits Research Institute for Malaria (Faculty of Health Sciences, University of the Witwatersrand) and The National Institute for Communicable Diseases (NICD). Her research is currently focused on exploring methods to genetically modify Anopheles mosquitoes in order to eliminate malaria transmission. Some of these methods include manipulation of the mosquito microbiota and generating gene knockouts using CRISPR. She is also interested in the role of epigenetics and the small RNA transcriptome of Anopheles mosquitoes.
Dr Chen completed her PhD in 2022 at the University of the Witwatersrand, in the School of Molecular and Cell Biology, where she evaluated the toxicity of Bacillus thuringiensis (Bt) Cry proteins (Cry1Ab, Cry1Ac, Cry1A.105 and Cry2Ab2.820) against fall armyworm (FAW), Spodoptera frugipera (J.E. Smith) in South Africa. The novel project aimed to evaluate whether current agriculturally important insecticidal bacterial proteins would be effective in controlling the newly invasive maize pest, FAW, in South Africa. In doing the research, she established one of the first FAW colonies in South Africa, two new toxicity bioassay techniques for FAW (one is published, and one is awaiting publication) and revealed that two Bt Cry proteins would be effective in bio-controlling FAW, thus setting the foundation for future FAW control strategies in South Africa. Thus, Dr Chen's expertise includes, but is not limited to, molecular and cell biology, microbiology, invertebrate pathology and medical entomology.
Research Interests
Papers共 16 篇Author StatisticsCo-AuthorSimilar Experts
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Reliability Physics Symposiumpp.3A.2.1-3A.2.6, (2011)
Digital Game and Intelligent Toy Enhanced Learningpp.222-224E, (2010)
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