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Our studies focus on understanding how muscle contraction is regulated at the level of the sarcomere in response to Ca2+ and how the regulation is altered in disease states. Most of our work has concentrated on two inherited heart disorders, hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM), both of which can be caused by mutations in genes that encode components of the contractile apparatus. More recently, we have started to investigate novel post-translational mechanisms and have begun work on disease mechanisms in inherited skeletal muscle myopathies.
Research Interests
Papers共 154 篇Author StatisticsCo-AuthorSimilar Experts
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biorxiv(2024)
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2023): 44-57
Olga E Karpicheva,Stanislava V Avrova, Andrey L Bogdanov,Vladimir V Sirenko,Charles S Redwood,Yurii S Borovikov
International journal of molecular sciencesno. 6 (2023): 5829-5829
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2022): S85-S86
Vasco Sequeira,Lili Wang,Paul J.M. Wijnker,Kyungsoo Kim,Jose R. Pinto,Cris dos Remedios,Charles Redwood,Bjorn C. Knollmann, Jolanda van der Velden
Journal of Molecular and Cellular Cardiology Plus (2022): 100007-100007
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