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Understanding the role of nutrition and the gut microbiome in physiology
Eminent immunologist Professor Charles Mackay is exploring an exciting new concept- that nutrition and the gut microbiome have profound influences on physiology, particularly immune responses (see Maslowski and Mackay, Nature Immunology 2009 and Thorburn, Macia and Mackay, Immunity 2014). Charles Mackay demonstrated that dietary fibre and its breakdown fermented products, the short chain fatty acids (SCFAs) influence gut homeostasis, the composition of the gut microbiota, immune tolerance, and inflammatory responses. His research focuses on cellular and molecular pathways, such as the 'metabolite-sensing GPCRs, and epigenetic pathways including HDAC inhibition.
Eminent immunologist Professor Charles Mackay is exploring an exciting new concept- that nutrition and the gut microbiome have profound influences on physiology, particularly immune responses (see Maslowski and Mackay, Nature Immunology 2009 and Thorburn, Macia and Mackay, Immunity 2014). Charles Mackay demonstrated that dietary fibre and its breakdown fermented products, the short chain fatty acids (SCFAs) influence gut homeostasis, the composition of the gut microbiota, immune tolerance, and inflammatory responses. His research focuses on cellular and molecular pathways, such as the 'metabolite-sensing GPCRs, and epigenetic pathways including HDAC inhibition.
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论文共 213 篇作者统计合作学者相似作者
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Cardiovascular research (2024)
JOURNAL OF HYPERTENSION (2023): E139-E139
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Journal of Hypertensionno. Suppl 1 (2023): e125-e125
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JOURNAL OF HYPERTENSION (2023): E125-E125
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Laurence Macia,Duan Ni,Jian Tan,Remy Robert,Jemma Taitz,Anjie Ge, Camille Potier-Villette, Julen Reyes,Alanna Spiteri,Claire Wishart,Charles Mackay,Laura Piccio,
Research Square (Research Square) (2023)
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