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个人简介
Dr. Chu's research focuses on mechanisms of neurodegeneration and neuroprotection in Parkinson's and related neurodegenerative diseases. A major focus is delineating why adaptive cellular mechanisms fail to protect neurons, with emphasis on mitochondrial dysfunction, alterations in kinase signaling and autophagy. Molecular and biochemical studies in cell culture and mouse models are integrated with studies of diseased human brain tissues. We are particularly interested in potentially reversible mechanisms by which mutations in PD-linked genes affect dendritic extension/retraction and synaptic dysfunction.
研究兴趣
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Autophagyno. 6 (2024): 1213-1246
Corneano. 2 (2023): 195-200
crossref(2023)
American Journal of Ophthalmology Case Reports (2022): 101599
The American journal of pathologyno. 2 (2022): 201-212
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