基本信息
浏览量:6
职业迁徙
个人简介
Research Interests
Molecular and cellular mechanisms of skeletal development, metabolism and regeneration
Molecular control of stem cell self-renewal and mesenchymal lineage differentiation
Tissue engineering for skeletal tissue repair
Efficacy and novel therapeutics of Chinese medicines for skeletal tissue repair
Publications
Chen X, Gu S, Chen BF, Shen WL, Yin Z, Xu GW, Hu JJ, Zhu T, Li G, Ouyang HW, Wan C, Lee TL, Chan WY (2015), Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway, Biomaterials. 53: 239-250.
Tian Y, Xu Y, Fu Q, Chang M, Wang Y, Shang X, Wan C, Marymont JV, Dong Y (2015), Notch inhibits chondrogenic differentiation of mesenchymal progenitor cells by targeting Twist1, Mol Cell Endocrinol. 403C:30-38.
Su X, Zuo W, Wu Z, Chen J, Wu N, Ma P, Xia Z, Jiang C, Ye Z, Liu S, Liu J, Zhou G, Wan C, Qiu G (2015), CD146 as a new marker for an increased chondroprogenitor cell sub-population in the later stages of osteoarthritis, J Orthop Res. 33(1):84-91.
Dai Z, Shu Y, Wan C, Wu C (2015), Effects of pH and thermally sensitive hybrid gels on osteogenic differentiation of mesenchymal stem cells, J Biomater Appl. 29(9):1272-83.
Zhang F, He Q, Tsang WP, Garvey WT, Chan WY, Wan C (2014), Insulin exerts direct, IGF-1 independent actions in growth plate chondrocytes, Bone Research 2(2): 14012.
Wan L, Zhang F, He Q, Tsang WP, Lu L, Li Q, Liu Z, Qiu G, Zhou G, Wan C (2014), EPO promotes bone repair through enhanced cartilaginous callus formation and angiogenesis, PLoS One (7):e102010.
Tsang WP, Shu Y, Kwok PL, Zhang F, Lee KKH, Tang MK, Li G, Chan KM, Chan WY, Wan C(2013), CD146 human umbilical cord perivascular cells maintain stemness under hypoxia and as a cell source for skeletal regeneration, PLoS One 8(10):e76153.
Yao D, Xie XH, Wang XL, Wan C, Lee YW, Chen SH, Pei DQ, Wang YX, Li G, Qin L (2012), Icaritin, an exogenous phytomolecule, enhances osteogenesis but not angiogenesis - an in vitro efficacy study, PLoS One 7(8):e41264.
Bian Q, Liang QQ, Wan C, Hou W, Li CG, Zhao YJ, Lu S, Shi Q, Wang YJ (2011), Prolonged upright posture induces calcified hypertrophy in the cartilage end-plate in rat lumbar spine, Spine (Phila Pa 1976). 36(24):2011-2020.
研究兴趣
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Jiawei Huang, Kin Pong U, Fuyuan Yang, Zeyuan Ji,Jiacheng Lin,Zhihui Weng,Lai Ling Tsang,Tobias D Merson,Ye Chun Ruan,Chao Wan,Gang Li,Xiaohua Jiang
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