Changjun Yang

My current research interests mainly focus on investigating molecular mechanisms involved in focal ischemic injury and developing novel therapeutic strategies for treatment of ischemic stroke. Specifically, I am interested in elucidating the roles of neuroinflammation and oxidative stress on mediating blood-brain barrier (BBB) integrity in ischemic stroke using in vitro cell cultures and in vivo models of transient and/or permanent middle cerebral artery occlusion (MCAO) in rats and mice.