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个人简介
The scientific activity of Cecilia Gelfi has been focused on:
- the development of methodologies for the separation and identification of biomolecules.
She contributed to the development of electrophoretic techniques transforming them into a physico-chemical tool for probing the structure and conformation of macromolecules;
- the investigation of the functional and morphological changes occurring in muscle in a number of physiological and pathological states. Since 1999 has contributed to the muscle proteome signature under physiological, paraphysiological and pathological conditions generating a database of differential changes in muscle proteomes both in humans and in animal models. These studies allowed: i) to define the interindividual variability of proteins expressed in specific muscles, ii) to identify proteomics profiles of different muscles (e.g. vastus lateralis, deltoideus, soleus, tibialis) associating them to muscle phenotypes;
- the development of 1) clinical methods for the monitoring of drugs; 2) protocols for serological profiles for the clinical diagnosis of pancreatic and prostate cancer; 3) MALDI imaging methodologies for monitoring nano particles; 4) HPTLC-MALDI methodologies for recognition and quantitation of gangliosides and globosides in tissue extracts.
- the development of methodologies for the separation and identification of biomolecules.
She contributed to the development of electrophoretic techniques transforming them into a physico-chemical tool for probing the structure and conformation of macromolecules;
- the investigation of the functional and morphological changes occurring in muscle in a number of physiological and pathological states. Since 1999 has contributed to the muscle proteome signature under physiological, paraphysiological and pathological conditions generating a database of differential changes in muscle proteomes both in humans and in animal models. These studies allowed: i) to define the interindividual variability of proteins expressed in specific muscles, ii) to identify proteomics profiles of different muscles (e.g. vastus lateralis, deltoideus, soleus, tibialis) associating them to muscle phenotypes;
- the development of 1) clinical methods for the monitoring of drugs; 2) protocols for serological profiles for the clinical diagnosis of pancreatic and prostate cancer; 3) MALDI imaging methodologies for monitoring nano particles; 4) HPTLC-MALDI methodologies for recognition and quantitation of gangliosides and globosides in tissue extracts.
研究兴趣
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EUROPEAN JOURNAL OF HUMAN GENETICS (2024): 229-229
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Forensic Science International (2023): 111774-111774
Stem cell research & therapyno. 1 (2023): 179-18
BMJ Openno. 10 (2023): e073163-e073163
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作者统计
#Papers: 241
#Citation: 9062
H-Index: 50
G-Index: 85
Sociability: 7
Diversity: 4
Activity: 60
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