基本信息
views: 0
Career Trajectory
Bio
Research activity:
Basic Medicine and Biomedicine – Study of molecular and cellular mechanisms associated with human pathologies:
1. Lysosomal storage diseases: study of immune system alterations in Mucopolysaccharidosis II and VI patients (2014–2015)
2. Alzheimer's disease: study of ABC transporters as amyloid-β clearance mechanisms in Alzheimer's disease mouse model (2017)
3. Aging: study of protein aggregation across lifespan in mice (2017–2018)
4. Nuclear envelopathies: study of LAP1's physiological role and contribution of its dysfunction to the development of human diseases (2017–Present)
Technical skills:
1. Cell culture and other related techniques: isolation of human peripheral blood mononuclear cells; production of Epstein-Barr virus (EBV) and establishment of EBV-transformed human B cell lines; mammalian cell culture (human fibroblasts, SH-SY5Y and HeLa cells); cell viability assays; transfection of mammalian cell lines
2. Cell biology: immunocytochemistry; fluorescence-activated cell sorting (FACS)
3. Molecular biology: bacterial transformation; plasmid DNA amplification and purification; genomic DNA isolation
4. Biochemistry: extraction and quantification of total protein in mammalian cell lines and mouse tissues; isolation of detergent-insoluble and soluble protein fractions; protein co-immunoprecipitation; subcellular fractionation of proteins; blot overlay assay; SDS-PAGE; immunoblotting; enzyme-linked immunosorbent assay (ELISA); agarose gel electrophoresis
5. Microscopy: epifluorescence and confocal microscopy
6. Bioinformatics: FlowJo, GraphPad Prism, Image Lab, ImageJ/Fiji, STRING, PANTHER, Cytoscape
Research Interests
Papers共 12 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Biochemistry and Biophysics Reports (2024): 101757-101757
Biology and Life Sciences Forumno. 1 (2023): 25
Tissue-Specific Cell Signalingpp.1-32, (2020)
AGING CELLno. 5 (2020): e13143-e13143
Load More
Author Statistics
#Papers: 16
#Citation: 172
H-Index: 6
G-Index: 13
Sociability: 4
Diversity: 0
Activity: 0
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn