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Research in Dr. Brisken’s laboratory focuses on the cellular and molecular underpinnings of estrogen and progesterone receptor signaling in the breast and the respective roles of these hormones and hormonally active compounds in carcinogenesis. The aim is to understand how recurrent exposures to endogenous and exogenous hormones contribute to breast carcinogenesis in order to better prevent and treat the disease. The laboratory has pioneered in vivo approaches to genetically dissect the role of the reproductive hormones in driving mouse mammary gland development and shown how they control intercellular communication. Dr. Brisken’s group has developed ex vivo and humanized mouse models using patient samples to study hormone action in human tissues in normal settings and during disease progression. Dr. Brisken is member of the International Breast Cancer Study Group (IBCSG) Biological Protocol Working Group. She served as Dean of EPFL Doctoral School (more than 2000 PhD students in 18 PhD programs), as member of the Hinterzartener Kreis, the oncology think-tank associated with the German Science Foundation, and numerous Swiss, European, and AACR committees.
研究兴趣
论文共 100 篇作者统计合作学者相似作者
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Tatjana Geukens,Maxim De Schepper,Wouter van den Bogaert,Karen Van Baelen, Marion Maetens, Anirudh Pabba, Amena Mahdami, Sophia Leduc, Edoardo Isnaldi, Ha-Linh Nguyen, Imane Bachir, Maysam Hajipirloo,
Yueyun Zhang, Carlos Henrique Venturi Ronchi,Giovanna Ambrosini, Yuanlong Liu,Patrick Aouad, Daria Matvienko, Christoph Merten,Cathrin Brisken
Cancer Researchno. 9_Supplement (2024): PO5-14
Binbin Gao,Elspeth Ward,Anna Blümel,Emer Conroy, Rachel Moore, Grainne Cremin,Rachel Bleach, Kathryn Haley,Tríona Ní Chonghaíle,Andreas Lindner,Jochen Prehn,Yi Zhang,
Cancer Researchno. 9_Supplement (2024): PO3-18
ENDOCRINOLOGYno. 5 (2024)
Siobhan Freeney, Helene Bonval, Esther Geven, Lori Petitti, Rian Terveer,Claire Turner,Cathrin Brisken,Patrick Derksen,Christine Desmedt,Thijs Koorman,ADRIAN LEE,Steffi Oesterreich,
Cancer Researchno. 9_Supplement (2024): PO2-11
crossref(2023)
Anne Boulay, Madlaina Breuleux, Christine Stephan, Caroline Fux,Cathrin Brisken,Maryse Fiche, Markus Wartmann,Michael Stumm,Heidi A. Lane,Nancy E. Hynes
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Anne Boulay, Madlaina Breuleux, Christine Stephan, Caroline Fux,Cathrin Brisken,Maryse Fiche, Markus Wartmann,Michael Stumm,Heidi A. Lane,Nancy E. Hynes
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