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职业迁徙
个人简介
The three major projects in the lab are:
(1) Hematopoiesis: We study mechanisms that regulate symmetrical selfrenewing hematopoietic stem cell (HSC) divisions (as observed in the fetal liver) vs.
(2) Pluripotent stem cell derived liver (hepatocytes and non-parenchymal liver cells) models: We are developing optimized differentiation schemes for hepatocytes from induced pluripotent stem cells, by evaluating the transcriptome, epigenome and metabolome of iPSC-derived hepatocytes in comparison with primary hepatocytes.
(3) Pluripotent stem cell derived neurodegeneration models: We and collaborators are creating models for neurodegenerative disorders (frontotemporal dementia, amyotrophic lateral sclerosis, Parkinson disease, Alzheimer disease and multiple sclerosis) using patient derived iPSC and CRISPR-mediated isogenic cells.
研究兴趣
论文共 676 篇作者统计合作学者相似作者
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Isaak Decoene,Gabriele Nasello,Rodrigo Furtado Madeiro de Costa,Gabriella Nilsson Hall, Angela Pastore,Inge Van Hoven, Samuel Ribeiro Viseu,Catherine Verfaillie,Liesbet Geris,Frank P. Luyten,Ioannis Papantoniou
STEM CELLS TRANSLATIONAL MEDICINEno. 3 (2024): 278-292
Inge Kinnart, Liselot Manders, Thibaut Heyninck,Dorien Imberechts,Roman Praschberger, Nils Schoovaerts,Catherine Verfaillie,Patrik Verstreken,Wim Vandenberghe
Yingli Zhu,Thibaut Burg, Katrien Neyrinck,Tim Vervliet,Fatemeharefeh Nami, Ellen Vervoort, Karan Ahuja,Maria Livia Sassano,Yoke Chin Chai,Arun Kumar Tharkeshwar,Jonathan De Smedt,Haibo Hu,
Acta Neuropathologicano. 1 (2024): 6-6
Science advancesno. 7 (2024): eadh8478-eadh8478
Yoke Chin Chai,San Kit To,Susan Simorgh,Samantha Zaunz, Yingli Zhu, Karan Ahuja, Alix Lemaitre,Roya Ramezankhani,Bernard K. van der Veer,Keimpe Wierda,Stefaan Verhulst,Leo A. van Grunsven,
ADVANCED SCIENCEno. 5 (2024): e2304421-e2304421
Gert Vanmarcke,Jonathan Sai-Hong Chui,Axelle Cooreman,Kristof De Vos, Lana Cleuren,Rob Van Rossom,Guillem García-Llorens,Teresa Izuel Idoype,Ruben Boon, Manoj Kumar Gautam,José V Castell,Pieter Annaert,
STEM CELLSno. 11 (2023): 1076-1088
Acta neuropathologicano. 2 (2023): 283-299
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