基本信息
浏览量:15
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
My laboratory studies the neurobiological mechanisms through which early environmental experiences are encoded and maintained into adulthood to have long-lasting impact on behavior. In particular, we are interested in understanding how early life stress increases risk for depression, addiction, and other psychiatric syndromes. This research is translationally motivated by the robust clinical finding that child maltreatment and other forms of early life stress increase the lifetime risk of depression and other mood, anxiety, and drug disorders by 2-4 -fold. Studies in humans and animals suggest that early life stress sensitizes individuals to exposures such as stress encountered later in life. To understand the neurobiological mechanisms underlying this latent behavioral vulnerability, we are integrating a range of technical approaches including rodent behavior, RNA and chromatin sequencing and bioinformatic analysis, in vivo cell-specific gene manipulation, and high-resolution imaging. By understanding how early life stress affects brain development at multiple levels - epigenetic and molecular, neuroendocrine, cells and circuits - we ultimately hope to apply such knowledge towards innovative therapies relevant to individuals who experienced childhood stress and trauma.
研究兴趣
论文共 87 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Luke T Geiger,Julie-Anne Balouek,Lorna A Farrelly, Andy S Chen, Megan Tang,Shannon N Bennett,Eric J Nestler,Benjamin A Garcia,Ian Maze,Catherine Jensen Peña
bioRxiv : the preprint server for biology (2024)
Nature Neuroscienceno. 2 (2024): 384-384
HORMONES AND BEHAVIOR (2024): 105472-105472
Heike Schuler, Rand S. Eid, Serena Wu, Yiu-Chung Tse,Vedrana Cvetkovska,Joëlle Lopez, Rosalie Quinn, Delong Zhou,Juliet Meccia,Laurence Dion-Albert,Caroline Menard, Shannon N. Bennett,
crossref(2024)
Hormones and behavior (2023): 105364-105364
Nature Neuroscienceno. 7 (2023): 1229-1244
Sero Toriano Parel,Shannon N Bennett, Cindy J Cheng, Olivia C Timmermans,Laura M Fiori,Gustavo Turecki,Catherine Jensen Peña
Proceedings of the National Academy of Sciences of the United States of Americano. 49 (2023)
NEURONno. 22 (2023): 3541-+
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn