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Dr Caruana is a Lecturer in Neuroscience and a synaptic neurophysiologist specialising in drug- and disease-related changes in brain chemistry affecting synapses and memory. It is widely accepted that experience-dependent modifications in synaptic function underlie information storage in the brain, and that modulatory neurotransmitter systems play a central role in regulating this neuroplasticity. A fundamental problem remains, though, in understanding how dysfunctions in neuromodulation linked to brain pathology (e.g., epilepsy or depression) or drug abuse alter synaptic mechanisms essential to cognition. Dr Caruana uses electrophysiology, pharmacology, molecular biology and behaviour to determine how modulatory neurotransmitters and nootropic compounds modify synapses in the hippocampus and parahippocampal cortices to affect sensory and mnemonic processing in both normal and diseased brains.
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JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGYno. 2 (2022): 183-193
Journal of Neural Transmissionno. 3 (2008): 401-411
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