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Biological membranes are essential for life. They provide specialized permeability barriers for cells and cell organelles, in which the interplay of lipids and membrane proteins enable fundamental processes of energy conversion, protein and solute transport, signal perception and transduction, and motility. The main facilitators of function are membrane proteins which also comprise the majority of drug targets. Protein structures are the basis for a complete understanding of mechanism of action and for elucidation of ligand binding. Yet, structures of membrane proteins in general and of eukaryotic and human membrane proteins in particular are still rare. In addition, little is known about interactions with lipids and intra-cellular signaling pathways critical for function.
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论文共 150 篇作者统计合作学者相似作者
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Journal of Biological Chemistryno. 6 (2024): 107331-107331
Nature methodsno. 7 (2024): 1340-1348
Florian Becker,Simon Fuchs,Lukas Refisch,Friedel Drepper,Wolfgang Bildl,Uwe Schulte,Shuo Liang,Jonas Immanuel Heinicke, Sierra C. Hansen,Clemens Kreutz,Bettina Warscheid,Bernd Fakler,
eLife (2023)
Florian Becker,Simon Fuchs,Lukas Refisch,Friedel Drepper,Wolfgang Bildl,Uwe Schulte,Shuo Liang,Jonas Immanuel Heinicke, Sierra C. Hansen,Clemens Kreutz,Bettina Warscheid,Bernd Fakler,
eLife (2023)
Suraj Patil,Oleg Borisov, Nora Scherer,Christophe Wirth,Pascal Schlosser,Matthias Wuttke, Kai-Uwe Eckardt,Carola Hunte, Björn Neubauer,Anna Köttgen,Michael Köttgen
medrxiv(2023)
crossref(2023)
Nature communicationsno. 1 (2023): 323-16
Laura F. Fielden,Jakob D. Busch,Sandra G. Merkt,Iniyan Ganesan,Conny Steiert, Hanna B. Hasselblatt,Jon V. Busto,Christophe Wirth,Nicole Zufall,Sibylle Jungbluth, Katja Noll,Julia M. Dung,
Natureno. 7979 (2023): 627-634
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