Chak Lui Carmen Wong(黃澤蕾)
副教授
Department of Pathology
School Clinical Medicine, The University of Hong Kong;Cancer Biology Lab, Faculty of Medicine, The University of Hong Kong;Centre for Oncology and Immunology, The University of Hong Kong;State Key Laboratory of Liver Research, The University of Hong Kong;Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong
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个人简介
she received the Croucher Foundation Fellowship and obtained her post-doctoral training from the Nobel Laureate, Professor Gregg Semenza, in the Johns Hopkins University, studying the roles and molecular mechanisms of hypoxia (oxygen deprivation) in breast cancer progression. Hypoxia is a common pathological feature in cardiovascular diseases, ischemia (e.g. stroke, limb, and retinal ischemia), and cancer. Hypoxia, through the stabilization of hypoxia-inducible factors (HIFs), stimulates a wide repertoire of events that promote cancer growth. Two hypoxia-mediated events that caught her attention include metabolic reprogramming and tumor microenvironment formation. After returning to Hong Kong, Dr. Wong became a principal investigator and her team is intensively studying these two research areas in a fatal cancer, hepatocellular carcinoma, which is particularly prevalent in hepatitis B virus endemic regions including Hong Kong. More excitingly, Dr. Wong’s research team is beginning to unravel the tight relationship between metabolic reprogramming and tumor microenvironment formation, two seemingly unrelated disciplines, in cancer development.
研究兴趣
论文共 107 篇作者统计合作学者相似作者
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Cheuk-Him Man,Wing Lam, Chee-Chean Dang,Xiao-yuan Zeng,Li-Chuan Zheng, Natalie Nok-Man Chan,Ka-Lam Ng,Koon-Chuen Chan,Tsz-Ho Kwok, Timothy Chi-Chun Ng,Wing-Yan Leung, Michael Shing-Yan Huen,
BLOODno. 23 (2023): 2002-2015
JCO precision oncology (2023)
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H. Zhang,C. C. L. Wong, H. Wei,D. M. Gilkes,P. Korangath, P. Chaturvedi,L. Schito,J. Chen,B. Krishnamachary,P. T. Winnard Jr,V. Raman,L. Zhen,
Cellular and molecular gastroenterology and hepatologyno. 1 (2023): 133-159
Hepatology communicationsno. 4 (2023)
MOLECULAR CANCER RESEARCHno. 10 (2023): 1120-1120
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