基本信息
浏览量:41
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
Research Interests
Professor Maley is a cancer biologist, evolutionary biologist and computational biologist, working at the intersection of those fields. His team applies evolutionary and ecological theory to three problems in cancer: (1) Neoplastic progression: the evolutionary dynamics among cells of a tumor that drive progression from normal tissue to malignant cancers, (2) Acquired therapeutic resistance: the evolutionary dynamics by which our therapies select for resistance and we fail to cure cancer, and (3) the evolution of cancer suppression mechanisms in large, long-lived animals like elephants and whales (a problem called Peto’s Paradox). They use genomic data mining, phylogenetics, computational modeling, as well as wet lab techniques to solve these problems. In all of this work, their goals are to develop better methods to prevent cancer and improve cancer management.
Professor Maley is a cancer biologist, evolutionary biologist and computational biologist, working at the intersection of those fields. His team applies evolutionary and ecological theory to three problems in cancer: (1) Neoplastic progression: the evolutionary dynamics among cells of a tumor that drive progression from normal tissue to malignant cancers, (2) Acquired therapeutic resistance: the evolutionary dynamics by which our therapies select for resistance and we fail to cure cancer, and (3) the evolution of cancer suppression mechanisms in large, long-lived animals like elephants and whales (a problem called Peto’s Paradox). They use genomic data mining, phylogenetics, computational modeling, as well as wet lab techniques to solve these problems. In all of this work, their goals are to develop better methods to prevent cancer and improve cancer management.
研究兴趣
论文共 289 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
bioRxiv the preprint server for biology (2024)
Diego Mallo, Pablo Bousquets-Munoz,Heather E. Grant,Darryl Shibata,Trevor A. Graham,Carlo C. Maley,Calum Gabbutt
CANCER RESEARCHno. 3 (2024)
Cancer Researchno. 6_Supplement (2024): 6184-6184
Merih D. Toruner,Luis Cisneros, Zafar Siddiqui, Chady Meroueh, Ritambhara Singh,Carlo Maley,Martin E. Fernandez-Zapico,Ryan M. Carr
CANCER RESEARCHno. 3 (2024)
CANCER RESEARCHno. 3 (2024)
Sareh Seyedi, Ruthanne Teo,Luke Foster,Daniel Saha,Lida Mina,Donald Northfelt, Karen S. Anderson,Darryl Shibata,Robert Gatenby,Luis H. Cisneros,Brigid Troan,Alexander R. A. Anderson,
CANCERSno. 2 (2024)
CANCER RESEARCHno. 3 (2024)
Zachary T Compton,Walker Mellon,Valerie Harris,Shawn Rupp,Diego Mallo,Stefanie Kapsetaki, Mallory Wilmot,Ryan Kennington, Kathleen Noble,Cristina Baciu, Lucia Ramirez,Ashley Peraza,
bioRxiv : the preprint server for biology (2024)
Heather E. Grant, Rachel Alcraft, Pablo Bousquets-Munoz,Calum Gabbutt,Alison Berner,Mehmet Yalchin,Carlo C. Maley,Trevor A. Graham,Diego Mallo
CANCER RESEARCHno. 3 (2024)
Bryan Yavari, Nilofar Kolbehdari, Lindsay Gann, Mercedes Portillo, Alexandria Rumschlag, Melaine Aldridge,Walker Mellon,Gissel Marquez Alcaraz, Harley Richker, Mané Sarkissian,Zachary T Compton,Athena Aktipis,
medRxiv : the preprint server for health sciences (2024)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn