基本信息
views: 433
Career Trajectory
Bio
Chris Wallace's research programme has three complementary aims. First, to develop the statistical tools needed to identify genetic associations with disease, then robustly and empirically link each genetic association with a gene, cell type, stimulatory condition and ultimately a biological pathway. Specifically, this requires methods for:
horizontal integration of different layers of omics data
mapping the variants which regulate gene expression
"fine mapping" causal genetic variants from amongst associated variants in genetic association data, typically using sparse variable selection
"fine mapping" regulatory contacts in 3D maps of folded DNA from technologies such as promoter capture Hi-C
horizontal integration of different layers of omics data
mapping the variants which regulate gene expression
"fine mapping" causal genetic variants from amongst associated variants in genetic association data, typically using sparse variable selection
"fine mapping" regulatory contacts in 3D maps of folded DNA from technologies such as promoter capture Hi-C
Research Interests
Papers共 223 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Wei-Yu Lin,Melissa Kartawinata,Bethany R Jebson,Restuadi Restuadi,CLUSTER Consortium, Lucy R Wedderburn,Chris Wallace
biorxiv(2024)
Melissa Kartawinata,Wei-Yu Lin, Beth Jebson, Kathryn O'Brien,Elizabeth Ralph,Restuadi Restuadi,George T Hall,Sergi Castellano,Chris Wallace, Lucy R Wedderburn
Desiré Casares-Marfil,Manuel Martínez-Bueno,Maria Orietta Borghi,Guillermo Pons-Estel, PRECISESADS Clinical Consortium,Guillermo Reales,Yu Zuo,Gerard Espinosa,Timothy Radstake, Lucas L van den Hoogen,Chris Wallace,Joel Guthridge,
Arthritis & rheumatology (Hoboken, N.J.) (2024)
bioRxiv (Cold Spring Harbor Laboratory) (2024)
Helen Ray-Jones, Zeji Song,Alexander Haglund, Pavel Artemov,Monica Della Rosa,Frances Burden,Roman Kreuzhuber, Anna Litovskikh, Vanessa Xue Hui Tan, Lai Ting Chan,Mattia Frontini,Chris Wallace,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
GUTno. SUPPL_3 (2023): A32-A33
Zenodo (CERN European Organization for Nuclear Research)no. 1 (2023)
CT Stankey,C Bourges, T Turner-Stokes, AP Piedade,C Palmer-Jones, I Papa, M Dos Silva dos Santos, LO Randzavola,L Speidel, EC Parkes,W Edwards,AP Rochford,
biorxiv(2023)
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn