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We are using the latest DNA sequencing technology to read the genetic makeup of cancer cells within tumours in ever greater detail, teasing out patterns of evolution (evolutionary rule books), cancer heterogeneity and working out what changes have happened as a tumour evolves. We’re also investigating the processes that cause mutations and accelerate tumour evolution and working out how they might be stopped. And we are running evolutionary clinical trials with immune and targeted therapies to bring the benefits of our work to patients as quickly as possible.
Research Interests
Papers共 637 篇Author StatisticsCo-AuthorSimilar Experts
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Katey S S Enfield,Emma Colliver,Claudia Lee,Alastair Magness, David A Moore, Monica Sivakumar,Kristiana Grigoriadis,Oriol Pich,Takahiro Karasaki,Philip S Hobson,Dina Levi,Selvaraju Veeriah,
Cancer discoveryno. 6 (2024): 1018-1047
CELLno. 7 (2024): 1617-1635
biorxiv(2024)
Christopher J. Sweeney, John D. Hainsworth, Ron Bose,Howard A. Burris,Razelle Kurzrock,Charles Swanton, Claire F. Friedman, David R. Spigel, Tania Szado, Katja Schulze, Richard Price, Julia Malato,
JOURNAL OF CLINICAL ONCOLOGYno. 3 (2024)
Hermaleigh Townsley, Joshua Gahir,Timothy W. Russell, David Greenwood,Edward J. Carr, Matala Dyke,Lorin Adams, Murad Miah,Bobbi Clayton, Callie Smith, Mauro Miranda,Harriet V. Mears,
PLOS ONEno. 3 (2024)
Giulia Dowgier,Agnieszka Hobbs, David Greenwood,Marianne Shawe-Taylor,Phoebe Stevenson-Leggett, James Bazire, Rebecca Penn,Ruth Harvey, Crick COVID serology pipeline, Legacy Investigators,Vincenzo Libri,George Kassiotis,Steve Gamblin,
crossref(2024)
Alastair Magness,Emma Colliver,Katey S. S. Enfield, Claudia Lee,Masako Shimato, Emer Daly,David A. Moore, Monica Sivakumar,Karishma Valand, Dina Levi, Crispin T. Hiley, Philip S. Hobson,
Nature Communicationsno. 1 (2024): 1-20
Marianne Shawe-Taylor, David Greenwood,Agnieszka Hobbs,Giulia Dowgier, Rebecca Penn,Theo Sanderson,Phoebe Stevenson-Leggett, James Bazire,Ruth Harvey,Vincenzo Libri,George Kassiotis,Steve Gamblin,
The Lancetno. 10432 (2024): 1133-1136
Iris H.R. Yoon,Robert Jenkins,Emma Colliver,Hanyun Zhang,David Novo,David Moore, Zoe Ramsden,Antonio Rullan,Xiao Fu,Yinyin Yuan,Heather A. Harrington,Charles Swanton,
biorxiv(2024)
Charles Swanton, Matthew Margolis,Earl Hubbell,Kathryn N. Kurtzman, Stephannie Shih,Oliver Venn, Michael Seiden
Cancer Researchno. 6_Supplement (2024): 3895-3895
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