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个人简介
Our laboratory is interested in signal transduction processes that activate the inducible transcription factor nuclear factor-κB (NF-κB) as well as in regulatory mechanisms that control the activity of NF-κB in the nucleus.
NF-κB and its regulators provide an excellent model system with broad physiological and medical significance. The transcription factor controls important steps in immunity and inflammation, as well as cell death, proliferation or metabolism. Its activity is controlled by inhibitory IκB proteins and the IκB kinase (IKK) complex.
NF-κB and its regulators provide an excellent model system with broad physiological and medical significance. The transcription factor controls important steps in immunity and inflammation, as well as cell death, proliferation or metabolism. Its activity is controlled by inhibitory IκB proteins and the IκB kinase (IKK) complex.
研究兴趣
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Cell Chemical Biologyno. 10 (2023): 1303-+
iScienceno. 10 (2023): 107917-107917
Nature communicationsno. 1 (2023): 6947-18
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