基本信息
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Bio
My research aims at understanding the molecular basis for biological function in two main areas. The first involves understanding how amino acid sequence controls protein structural dynamics using pressure perturbation combined with state-of-the-art biophysical techniques. This is important information for protein design strategies for bio-pharmaceutics and for bio-engineering applications, as well as for understanding the evolution of protein sequences and life in extreme environments. The second area of research that I pursue involves characterizing, quantitatively, the protein interactions implicated in the regulation of gene expression. Currently we are trying to understand the links between cell growth and division in the model organism, budding yeast by applying advanced quantitative microscopy approaches. Understanding what drives cells to divide is important for understanding and developing therapeutic strategies for the treatment of many diseases, including cancer.
Research Interests
Papers共 299 篇Author StatisticsCo-AuthorSimilar Experts
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iScienceno. 3 (2025): 112027-112027
Biophysical Journalno. 3 (2024): 197a-197a
Biophysical Journalno. 3 (2024): 222a-222a
Carleton H. Coffin,Luke A. Fisher, Sara Crippen, Phoebe Demers,Douglas H. Bartlett,Catherine A. Royer
FRONTIERS IN MICROBIOLOGY (2024)
Biophysical Journalno. 3 (2024): 223a-223a
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Author Statistics
#Papers: 299
#Citation: 9460
H-Index: 54
G-Index: 90
Sociability: 7
Diversity: 3
Activity: 19
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