基本信息
views: 38
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Prof. Cinzia Marchese is Full Professor of Laboratory's Medicine MED/46 at the Faculty of Medicine of the University Sapienza of Rome. She was born in Catania, where she obtained the degree in Biology in 1982, the specialty in Pathology in 1987, and the PhD in Immunopharmacology in 1992. She was PhD Scientist at the Harvard Medical School in Boston in the Laboratory of Prof. H. Green to learn the methodology of primary cultures of human keratinocytes, for application in severe burn wounds. Then she spent several periods of times at the National Institute of Health in the Laboratory of Prof. S.A. Aaronson for a still going collaboration on the study of the role of growth factors and their receptors in the regulation of cellular proliferation and differentiation pathways.
In particular she focused her research interest on the analysis of the molecular and functional significance of the keratinocyte growth factor (KGF) and its receptor and their involvement in skin reepithelialization and wound healing process. She investigated also the distribution and dynamics following activation of KGFR and during internalization and down-regulation of ligand-receptor complexes and the modulation of the expression of receptors and proliferation or differentiation markers in primary human cultured keratinocytes.
Recently she developed a new technique for in vitro reconstruction of neovaginal tissue, in the treatment of patients with Mayer Rokitansky Kuster Hauser Sindrome, characterized by vaginal agenesis with variable mullerian duct abnormalities. This work has led to introduction worldwide of effective new surgical treatment protocols in reconstruction of vaginal tissue, that could also serve for other conditions such as vaginal trauma squeal or vaginoplasty in patients’ subjected to pelvic exenteration.
She also has contribuled to the regenerative medicine field by generating an in vitro skin substitute harbouring autologous fibroblasts, keratinocytes and melanocytes, to establish a new one-step clinical method in the treatment of problems associated with skin disorders as congenital giant melanocytic nevi. This work was recognized for the efforts to gain a better understanding of some of the markers associated to the risk of transformation into malignant melanoma.
Research Interests
Papers共 122 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Matteo Cassandri, Antonella Porrazzo,Silvia Pomella, Simona Camero, Francesca A. Aiello, Lucrezia D'Archivio,Clemens Zwergel,Beatrice Noce, Miriam Tomaciello,Francesca Vulcano, Luisa Milazzo, Francesca Pedini,
Simona Camero,Luisa Milazzo,Francesca Vulcano, Federica Ceccarelli,Paola Pontecorvi,Francesca Pedini,Alessandra Rossetti, Elena Sofia Scialis,Giulia Gerini, Fabrizio Cece,Silvia Pomella,Matteo Cassandri,
BMC Cancerno. 1 (2024): 1-24
TISSUE ENGINEERING PART Ano. 11-12 (2023): 380-381
Cited0Views0Bibtex
0
0
Journal of translational medicineno. 1 (2023): 1-15
Research Square (Research Square) (2023)
BRITISH JOURNAL OF HAEMATOLOGYno. 2 (2023): e12-e15
Paola Pontecorvi,Simona Ceccarelli, Fabrizio Cece,Simona Camero,Lavinia Vittoria Lotti,Elena Niccolai,Giulia Nannini,Giulia Gerini,Eleni Anastasiadou, Elena Sofia Scialis,Enrico Romano,Mary Anna Venneri,
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 14 (2023): 11379-11379
S. Camero,L. Milazzo,F. Vulcano, F. Pedini,P. Pontecorvi, G. Gerini,S. Ceccarelli,E. Anastasiadou, S. Pomella, M. Cassandri, A. Porrazzo, R. Rota,
ESMO Openno. 1 (2023): 101142-101142
Paola Pontecorvi, Simona Ceccarelli, Fabrizio Cece,Simona Camero,Lavinia Vittoria Lotti,Elena Niccolai,Giulia Nannini, Giulia Gerini,Eleni Anastasiadou, Elena Sofia Scialis, Enrico Romano,Mary Anna Venneri,
International Journal of Molecular Sciencesno. 14 (2023): 11379
crossref(2023)
Load More
Author Statistics
#Papers: 122
#Citation: 3094
H-Index: 30
G-Index: 51
Sociability: 6
Diversity: 0
Activity: 1
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn