基本信息
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个人简介
Seasoned, forward-thinking, highly skilled Manager with broad experience in different areas of pharmaceutical development.
Trained as immunologist (PhD in immunopharmacology and immunotoxicology) with large experience in preclinical and clinical investigations in different disease areas: infectious diseases, autoimmune diseases and osteoarthritis. Several years of industry experience with different companies in leading positions (GlaxoWellcome/GSK, Bayer, MerckSerono/Merck KGaA). Involved in in-licensing/due-diligence activities.
Clinical research experience: Focus over the last >15 years in research and development of therapies in immunology, rheumatology and osteoarthritis. Special interest in personalized medicine and stratification approaches in clinical development, using different types of biomarkers and imaging techniques. Several patents with focus on clinical strategies.
Collaboration management: Responsible for international collaborations in non-clinical as well as clinical settings. Involved in different public-private initiatives (e.g. FNIH/OARSI, IMI APPROACH) with focus on qualification and validation of biomarkers. Focus on “How to effectively design Clinical Trials using smart Data & digital tools”. Workpackage lead in a PPP where machine learning is applied to big data from available consortia to identify a patient phenotype and apply this in prospective selection of patients.
Project management: Project lead in several projects from early research up to phase II clinical trials. Core team member of several programs with focus on translational aspects and clinical biomarker strategies.
Operational actvities: Planning (incl. budget forecast and actuals) for programs and portfolios in defined therapeutic areas
Consultancy: Provide consultancy for early clinical development strategies, incl. translational approaches for different entities. Evaluation of research grant applications for Arthritis Foundation US and ReumaNederlands
AREAS OF EXPERTISE
• Preclinical and clinical development
• Translational Research, incl. imaging in clinical trials.
• Involved in design and execution of clinical studies from phase I to phase III. Implementation lead for stratification approaches in clinical studies
• Biomarker strategies
• Portfolio responsibility and management, incl. budget and strategic planning
• Business development and in-licensing of projects up to clinical phase III
• Project Management/Project Leadership: Working in and with multi-national and cross-functional programs/teams
• Collaboration management (national and international)
研究兴趣
论文共 149 篇作者统计合作学者相似作者
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Felix Eckstein,Anna Wisser,Susanne Maschek,Wolfgang Wirth,Christoph Ladel,Asger R. Bihlet, Chris Knight, Luping Zhao
Osteoarthritis and Cartilage (2024): S21-S22
ACR OPEN RHEUMATOLOGYno. 4 (2024): 205-213
Felix Eckstein,Anna Wisser,Susanne Maschek,Wolfgang Wirth,Christoph Ladel,Asger Reinstrup Bihlet, Chris Knight, Kenneth Somberg, Luping Zhao
Osteoarthritis and Cartilage (2024)
Heng-Zhen Li, Jing-lve Zhang,Dong-Liang Yuan,Wen-Qing Xie,Christoph H. Ladel,Ali Mobasheri,Yu-Sheng Li
MILITARY MEDICAL RESEARCHno. 1 (2024): 40-40
Jamie E. Collins,Peter Mesenbrink, Rui Jin,Erik Dam,Leticia A. Deveza,Felix Eckstein,Thomas Fuerst,Ali Guermazi,Christoph Ladel,Elena Losina,Thomas A. Perry, Douglas Robinson,
Osteoarthritis and cartilage (2024): S110-S111
Monica T. Hannani,Christian S. Thudium, Alfred C. Gellhorn,Jonathan Larkin,Christoph Ladel,Cecilie Bager,Morten Karsdal,André Struglics, Florian Lafeber,Simon Mastbergen,Melanie Uebelhoer,Francisco J Blanco-Garcia,
Osteoarthritis and Cartilage (2024): S57-S58
Osteoarthritis and cartilage (2024): S125-S125
Osteoarthritis and cartilageno. 2 (2023): 238-248
Osteoarthritis and Cartilage (2023): S263-S265
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作者统计
#Papers: 149
#Citation: 4255
H-Index: 33
G-Index: 64
Sociability: 6
Diversity: 3
Activity: 34
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