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We want to understand the mechanics of evolution. Exactly what molecules change? In what ways are these changes beneficial (or not) to the organism? How does this relate to what happens in populations of organisms? We mostly answer these questions using microbes. This means that our work relates to issues from the rise of antimicrobial resistance (AMR) to the roles of microbiomes – the mixed populations of microbes in particular places, from soil to our guts. Microbes reproduce fast enough that we can watch evolution happening in real time on the lab bench. To make sense of what’s going on we use computational models. Our mixture of wet-lab and computational approaches means that we collaborate both with other biologists, contributing quantitative approaches, as well as computer scientists and theoreticians.
Research Interests
Papers共 94 篇Author StatisticsCo-AuthorSimilar Experts
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Nishal Govindji-Bhatt,Stephnie M. Kennedy, Michael G. Barker, Darren Kell, Duncan Henderson, Nicholas Goddard, Ana Yepes Garcia, Adam S. Milner, Tom Willett, Ryan Griffiths, Peter Foster, William Kilgallon,
KIDNEY INTERNATIONAL REPORTSno. 3 (2024): 589-600
Microbiology (Reading, England)no. 4 (2024)
Zahraa Al-Baqsami, Rebecca Lowry Palmer, Gwyneth Darwent,Andrew J McBain,Christopher G Knight,Danna R Gifford
Journal of visualized experiments : JoVE (2024)
biorxiv(2024)
biorxiv(2023)
ONE EARTHno. 11 (2023): 1523-1541
Frontiers in Microbiomes (2023)
Rowan Green, Hejie Wang, Carol Botchey, Nancy Zhang, Charles Wadsworth,Andrew J McBain,Pawel Paszek,Rok Krašovec,Christopher G Knight
biorxiv(2023)
Danna R Gifford,Ernesto Berríos-Caro,Christine Joerres, Marc Suñé, Jessica H Forsyth,Anish Bhattacharyya,Tobias Galla,Christopher G Knight
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