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个人简介
My research focus is on medicinal chemistry of membrane proteins. We are interested in purinergic receptors and related G protein-coupled orphan receptors including G proteins, as well as ectonucleotidases involved in purinergic signal transduction. A broad spectrum of methods is utilized for our research projects including chemical synthesis of bioactive molecules and labelled compounds (molecular probes), (bio)analytical studies, assay development, structure analysis of drug-protein complexes, in vitro pharmacology, and molecular biology. In vivo studies of our compounds are performed in collaboration with colleagues in biology and medicine. My group runs two platforms, a chemical analytics platform with a focus on quantitative analysis, and a compound library with a unique collection of small synthetic molecules and natural products.
研究兴趣
论文共 793 篇作者统计合作学者相似作者
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Scientific reportsno. 1 (2024): 118-118
Philipp Flury,Julian Breidenbach,Nadine Krüger,Rabea Voget,Laura Schäkel, Yaoyao Si,Vesa Krasniqi, Sara Calistri, Matthias Olfert,Katharina Sylvester,Cheila Rocha, Raphael Ditzinger,
ACS pharmacology & translational scienceno. 2 (2024): 493-514
Julian Breidenbach,Rabea Voget, Yaoyao Si, Alexandra Hingst,Tobias Claff,Katharina Sylvester,Valentina Wolf,Vesa Krasniqi, Abibe Useini,Norbert Straeter,Yukino Ogura,Atsushi Kawaguchi,
JOURNAL OF MEDICINAL CHEMISTRYno. 11 (2024): 8757-8790
Tobias Claff, Andhika B Mahardhika,Victoria J Vaaßen,Jonathan G Schlegel,Christin Vielmuth,Renato H Weiße,Norbert Sträter,Christa E Müller
ACS pharmacology & translational scienceno. 5 (2024): 1415-1425
Philipp Flury,Julian Breidenbach,Nadine Krüger,Rabea Voget,Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert,Katharina Sylvester,Cheila Rocha, Raphael Ditzinger,
ACS pharmacology & translational scienceno. 4 (2024): 1195-1196
Ghazl Al Hamwi,Vigneshwaran Namasivayam, Beatriz Büschbell,Robin Gedschold,Stefan Golz,Christa E. Müller
Communications biologyno. 1 (2024): 52-52
Yuki Yamauchi,Sho Konno, Noriko Omura, Narumi Yoshioka, Alexandra Hingst,Michael Gütschow,Christa E Müller,Akihiro Taguchi,Atsuhiko Taniguchi,Atsushi Kawaguchi,Yoshio Hayashi
Hai-Jun Zhang,Michał Ociepa,Molhm Nassir,Bin Zheng,Sarah A. Lewicki,Veronica Salmaso, Helay Baburi,Jessica Nagel,Salahuddin Mirza,Beatriz Bueschbell,Haneen Al-Hroub, Olga Perzanowska,
Nature Chemistryno. 2 (2024): 249-258
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