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Bio
Graduated in Biological Science at University of Rome “La Sapienza” in 2001. From February 2002 to September 2005, I worked at the Nuclear Medicine Department of Policlinico “Umberto I” in Rome, attending at the development of new radiopharmaceuticals (peptides, monoclonal antibodies and cytokines based) labelled with 125I, 123I, 124I and 99mTc for in vitro and in vivo study of chronic inflammatory processes and oncological diseases.
From 2002 to 2006, I participated to the following research projects supported by several fundings:
1) as co-PI of Strategic scientific project CNR-MIUR "Oncology" (fund: 02.00388.ST97) entitled: "Labeling of TSH derived peptides for the in vivo diagnosis of differentiated thyroid tumors metastases".
2) as co-PI of Project of National Council of Research (CNR) “Young Researcher” entitled: “Radiolabelled Cytokines for the in vivo visualization of chronic inflammatory processes: in vitro and in animals studies”.
3) as PI of the Project Awarded by Italian Society of Rheumatolgy entitled: “Use of a 99mTc-labelled anti-TNFalpha monoclonal antibody in Rheumatoid arthritis: in vitro and in vivo studies".
4) as PI of Project "Nuvion" supported by PDL BioPharma, Nevada USA, entitled: “Study of in vivo biodistribution of 99mTc-labeled Nuvion in patients with Ulcerative Colitis”.
5) Project supported by Italian Association for Cancer Research (AIRC) 2003, entitled: “Use of radiolabeled TSH for diagnosis and therapy of metastatic differentiated thyroid cancer (DTC)”.
6) as co-PI of the Project supported by Italian Association for Cancer Research (AIRC) 2004, entitled: “In vivo detection of CXCR4 and CCR7 in breast cancer using radiolabeled ligands”.
From 2012, co-principal investigator for the project “Development of clinically implementable imaging strategies for in vivo monitoring of tumor-reactive T cell receptor-transgenic T cells” in the context of the Collaborative Research Centre 824 (SFB 824) of the Deutsche Forschung Gemainschaft (DFG).
In 2002 and 2003 I attended to a Short Term Scientific Mission within the COST B12 scientific programme at Nuclear Medicine Research Laboratory, at the Imperial Cancer Research Foundation, St. Bartholomew's Hospital London UK under the supervision of Prof. S.J. Mather focussing on radiolabelling the recombinant human IL-2 with 99mTc using bifunctional ligands for imaging chronic inflammatory diseases.
In 2004 I attended to a Short Term Scientific Mission at the Institut der Nuklearmedizin Radiologiche Chemie – Labor Kantonsspital, Basel Switzerland, under the supervision of Prof. H. R. Mäcke to radiolabel peptides for imaging chronic inflammatory diseases using the technetium-organometallic Tc(CO)3 technique.
From 2006 to 2007 I attended at the radiolabeling of autologous leucocytes with 99mTc and 18F-FDG for studing inflammatory diseases and imaging infected vascular prosthesis and to routine synthesis of 90Y-Zevalin for treatment of patients affected by NHL, in the Department of Nuclear Medicine at Sant’Andrea Hospital in Rome.
At 21th of May 2007 I achieved the title of PhD in Physiopathology and Radioisotopic defending my thesis entitled “Imaging Use of a 99mTc-labelled anti-TNF monoclonal antibody in Rheumatoid arthritis: in vitro and in vivo studies.”
Since 2007, I’m working as clinical resident researcher at the Nuclear Medicine Department of the Klinikum rechts der Isar in München (Germany) and I’m Laboratory manager and responsible person for the preparation and relative quality controls of radiopharmaceuticals used for PET imaging and therapy of neuroendocrine tumours (177Lu-Dota-Tate, 68Ga-Dota-TOC) and lymphoma diseases (90Y-Zevalin, 111In-Zevalin).
21 research articles, four reviews and two book chapters are to my credits in addiction to invited oral presentations at the Annual International Congress of the European Society of Radiopharmacy and Radiopharmaceuticals and at the Annual European Congress of Nuclear Medicine.
I attended several courses of improvement to complete my working and scientific profile:
In 2012: GMP-Basis training course for pharmaceutical quality assurance and drug safety provided by “Concept Heidelberg”, Heidelberg
In 2011: Advance Certificate in Preclinical Imaging in the contest of “Module IV of the Curriculum – Preclinical Imaging in Small Laboratory Animal”, Bregenz
In 2011: Qualification/Validation in Analytical Procedures (GMP-Basis training) provided by Analytik-Service - Dr. T. Trantow, Schöneiche, Berlin
In 2009: GMP-Basis training on pharmaceutical quality control provided by Analytik-Service - Dr. T. Trantow, Schöneiche, Berlin
In 2005 I attended to a course on “GMP in manipulating stem-cells in therapy” in Rome.
In 2006 I attended to a National Course on “The use of GCP in the development and in Clinical Trial of new drugs” organized by AIFA (Italian Agency for Pharmaceutical).
Research Interests
Papers共 153 篇Author StatisticsCo-AuthorSimilar Experts
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EJNMMI radiopharmacy and chemistryno. 1 (2024): 1-14
EJNMMI RADIOPHARMACY AND CHEMISTRYno. 1 (2024)
European Journal of Nuclear Medicine and Molecular Imagingpp.1-11, (2024)
The Journal of Nuclear Medicineno. 11 (2023): 1765-1771
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGINGno. SUPPL 1 (2023): S69-S69
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crossref(2023)
JOURNAL OF NUCLEAR MEDICINEno. 8 (2023): 1244-1251
Nuklearmedizin-nuclear Medicine (2023)
Nuklearmedizin-nuclear Medicine (2023)
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