基本信息
浏览量:119
职业迁徙
个人简介
The main focus of my translational research laboratory is to develop RNA based therapeutic agents for the potential treatment of a range of diseases. To this end, we have and will continue to take advantage of the fact that RNA is not just a passive carrier of genetic instructions inside of cells during the conversion of information from DNA to RNA to protein. Rather, RNA is an extremely versatile biological macromolecule. Certian RNAs can bind to specific protiens with high affinities, while others can for catalytic centers and perform enzymatic reactions. These facets of RNA coupled with the ease with which RNA can be manipulated in vitro make it a very powerful and unique therapeutic agent whose potential is largely untapped. Durring our endeavors, we plan to work closely with the members of the Molecular Therapeutics program as well as other faculty at the Duke University Medical Center to expedite the development and testing of these therapeutics.
研究兴趣
论文共 277 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Journal of Biological Chemistryno. 3 (2024)
Haixiang Yu,Shekhar Kumar,James W Frederiksen, Vladimir N Kolyadko,George Pitoc,Juliana Layzer,Amy Yan,Rachel Rempel, Samuel Francis,Sriram Krishnaswamy,Bruce A Sullenger
Nature communicationsno. 1 (2024): 3977-3977
Nucleic acid therapeuticsno. 1 (2024): 12-17
Cell chemical biologyno. 8 (2023): 879-892.e5
STAR Protocolsno. 3 (2023): 102348-102348
Shahid M Nimjee,Debra Wheeler, Stacy Nelson, Richard J Shea,Taegen Sullivan,Christina Mayer, Leo Pavliv,Juliana M Layzer, Jason Lickliter,Bruce Sullenger,Bruce Campbell,Richard C Becker
Bethany Powell Gray, Linsley Kelly,Kady-Ann Steen-Burrell, Juliana M. Layzer,Rachel E. Rempel, Shahid M. Nimjee,Brian C. Cooley, Alice F. Tarantal,Bruce A. Sullenger
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn