基本信息
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个人简介
Dr. Brown's laboratory has focused on the identification of gene defects that elucidate the molecular pathogenesis of selected neuromuscular diseases including amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), muscular dystrophy, adrenoleukodystrophy, hereditary neuropathy and hyperkalemic periodic paralysis. Knowledge of theses disease genes has facilitated the creation of mouse and cell-based models of these disorders. In turn, these resources have allowed study of therapeutic strategies using conventional small molecule approaches and new modalities such as inhibitory RNAi.
研究兴趣
论文共 380 篇作者统计合作学者相似作者
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Gene Therapyno. 3-4 (2024): 105-118
James W. Gilbert,Zachary Kennedy, Bruno M.D.C. Godinho,Ashley Summers,Alexandra Weiss,Dimas Echeverria, Brianna Bramato,Nicholas McHugh, David Cooper, Ken Yamada,Matthew Hassler,Hélène Tran,
Molecular Therapy - Nucleic Acidsno. 3 (2024): 102291
Alexandra Weiss,James W Gilbert, Iris Valeria Rivera Flores,Jillian Belgrad,Chantal Ferguson,Elif O Dogan,Nicholas Wightman, Kit Mocarski,Dimas Echeverria,Ashley Summers,Brianna Bramato,Nicholas McHugh,
bioRxiv : the preprint server for biology (2024)
Nature Communicationsno. 1 (2024): 1-2
NEUROBIOLOGY OF DISEASE (2024): 106414-106414
Stacy R. Lindborg,Namita A. Goyal,Jonathan Katz,Matthew Burford, Jenny Li, Haggai Kaspi,Natalie Abramov, Bruno Boulanger, James D. Berry,Katharine Nicholson,Tahseen Mozaffar, Robert Miller,
Frontiers in neuroscience (2023): 1251228-1251228
Handbook of clinical neurology (2023): 203-229
Elif O. Dogan,James Bouley,Jianjun Zhong, Ashley L. Harkins,Allison M. Keeler,Daryl A. Bosco,Robert H. Brown,Nils Henninger
Acta neuropathologica communicationsno. 1 (2023)
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作者统计
#Papers: 378
#Citation: 37319
H-Index: 93
G-Index: 188
Sociability: 8
Diversity: 0
Activity: 2
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