基本信息
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Career Trajectory
Bio
The theme of the laboratory (Program in Membrane Biology, PMB) is to understand how membrane transport vesicles interact with accessory proteins (GTPases, SNAREs, kinases) and with the cytoskeleton (microtubules, actin, and PDZ proteins) to modulate cell function via various membrane transport proteins in physiological and pathophysiological conditions. Experimental models used range from in vitro systems using purified proteins and membrane vesicles (endosomes, Golgi, plasma membrane), to transfected cell cultures, to whole animal models including transgenic mice. All projects are interactive and involve cell biological procedures such as confocal and EM-gold immunocytochemistry, real time confocal and TIRF microscopy. In addition, molecular and biochemical procedures are combined with cell biology to provide a multidisciplinary approach to problem solving. The aim of the research is to understand how physiologically-relevant processes of fluid and electrolyte transport across epithelia are regulated at the cell and molecular levels in kidney, the male reproductive tract and other organ systems.
Research Interests
Papers共 273 篇Author StatisticsCo-AuthorSimilar Experts
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Physiologyno. S1 (2024)
Truyen D. Pham,Jill W. Verlander,Chao Chen,Vladimir Pech, Hailey I. Kim, Young Hee Kim,I. David Weiner,Ginger L. Milne,Roy Zent,Fabian Bock,Dennis Brown,Amity Eaton,
Function (Oxford, England)no. 4 (2024)
Physiologyno. S1 (2024)
Ferran Barrachina,Kiera Ottino, Maia Lina Elizagaray,Maria Gracia Gervasi, Leona J. Tu,Styliani Markoulaki,Raul G. Spallanzani,Diane Capen,Dennis Brown,Maria Agustina Battistone
PHYSIOLOGY (2023)
biorxiv(2022)
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Author Statistics
#Papers: 270
#Citation: 21105
H-Index: 78
G-Index: 138
Sociability: 7
Diversity: 3
Activity: 94
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