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个人简介
Dr. D. Brian Foster graduated from Queen's University in Kingston, Ontario, with a Ph.D. in biochemistry under Dr. Jennifer Van Eyk. He moved to Boston where he received an American Heart Association Postdoctoral Fellowship to study biophysics and biochemistry of the "stunned" heart. Dr. Foster came to The Johns Hopkins School of Medicine, Division of Cardiology seeking new opportunities to further advance his training in biochemistry. As a junior faculty Research Associate, he spent much of his time searching for the identity of the elusive MitoKATP channel, whose activity wards off cell death by necrosis during and after a heart attack. It was at this time that Dr. Foster began to embrace the techniques and technologies of proteomics that ultimately led to the discovery mitoROMK - the strongest candidate yet for the pore-forming subunit MitoKATP. In a parallel effort, Dr. Foster teamed up with Dr. Anthony Cammarato to conduct the first ever proteomic analysis of the cardiac tube of the fruit fly, Drosophila melanogaster, which was hailed as a “Top 10 Advance" in 2011 by the Functional Genomics and Translational Biology Council of the American Heart Association.
As an Assistant Professor, in the Division of Cardiology, Brian continues to integrate the tools of protein biochemistry and proteomics. Core projects include further efforts to unravel the role of mitoROMK in cardioprotection. He is also investigating how networks of proteins and their post-translational modifications are perturbed in cardiomyopathy and heart failure.
As an Assistant Professor, in the Division of Cardiology, Brian continues to integrate the tools of protein biochemistry and proteomics. Core projects include further efforts to unravel the role of mitoROMK in cardioprotection. He is also investigating how networks of proteins and their post-translational modifications are perturbed in cardiomyopathy and heart failure.
研究兴趣
论文共 115 篇作者统计合作学者相似作者
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Axel J Fenwick, Vivek P Jani,D Brian Foster, Thomas E Sharp,Traci T Goodchild, Kyle LaPenna,Jake E Doiron, David J Lefer,Joseph A Hill, David A Kass,Anthony Cammarato
Deepthi Ashok,Ting Liu,Joseph Criscione,Meghana Prakash,Byunggik Kim, Julian Chow, Morgan Craney,Kyriakos N Papanicolaou,Agnieszka Sidor,D Brian Foster,Andrew Pekosz,Jason Villano,
bioRxiv : the preprint server for biology (2024)
Lorien G. Salyer,Hussam E. Salhi,Elizabeth A. Brundage,Vikram Shettigar,Sarah L. Sturgill, Helena Zanella, Benjamin Templeton,Eaman Abay, Kathryn M. Emmer,Jeovanna Lowe,Jill A. Rafael-Fortney,Narasimham Parinandi,
CIRCULATION RESEARCHno. 1 (2024): 33-45
Kyriakos N. Papanicolaou,Jessica Jung, Wenxi Zhang,Deepthi Ashok,D. Brian Foster, Brian O’Rourke,Natasha E. Zachara
Circulation Researchno. Suppl_1 (2023)
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The journals of gerontology. Series A, Biological sciences and medical sciencesno. 10 (2023): 1740-1752
Ting Liu,Deepthi Ashok, Morgan Craney,Amanda Wong,D. B. Foster,Andrew Pekosz,Jason Villano, Brian O'Rourke
CIRCULATION RESEARCHno. Suppl_1 (2023)
CIRCULATION RESEARCHno. Suppl_1 (2023)
Deepthi Ashok,Ting Liu,Devin B. Mair, Laila Stoddart,Kyriakos N. Papanicolaou,D. Brian Foster,Jason Villano, Deok Ho Kim, Brian O’Rourke
Circulationno. Suppl_1 (2022)
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