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个人简介
Kobilka is best known for his research on the structure and activity of G protein-coupled receptors (GPCRs); in particular, work from Kobilka's laboratory determined the molecular structure of the β2-adrenergic receptor. This work has been highly cited by other scientists because GPCRs are important targets for pharmaceutical therapeutics, but notoriously difficult to work with in X-ray crystallography. Before, rhodopsin was the only G-protein coupled receptor where the structure had been determined at high resolution. The β2-adrenergic receptor structure was soon followed by the determination of the molecular structure of several other G-protein coupled receptors.
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论文共 616 篇作者统计合作学者相似作者
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Evan S O'Brien, Vipin Ashok Rangari,Amal El Daibani, Shainnel O Eans, Haylee R Hammond, Elizabeth White,Haoqing Wang,Yuki Shiimura,Kaavya Krishna Kumar, Qianru Jiang,Kevin Appourchaux,Weijiao Huang,
Naturepp.1-8, (2024)
Natureno. 8013 (2024): 951-956
Marina Casiraghi,Haoqing Wang,Patrick Brennan,Chris Habrian,Harald Hubner,Maximilian F Schmidt,Luis Maul,Biswaranjan Pani, Sherif Mfm Bahriz,Bing Xu, Elizabeth White,Roger K Sunahara,
bioRxiv : the preprint server for biology (2024)
Jiawei Zhao,Matthias Elgeti,Evan S O'Brien,Cecília P Sár, Amal Ei Daibani,Jie Heng,Xiaoou Sun, Elizabeth White,Tao Che,Wayne L Hubbell,Brian K Kobilka,Chunlai Chen
Natureno. 8013 (2024): E13-E13
Hossein Batebi,Guillermo Pérez-Hernández, Sabrina N Rahman,Baoliang Lan, Antje Kamprad, Mingyu Shi,David Speck,Johanna K S Tiemann,Ramon Guixà-González,Franziska Reinhardt,Peter F Stadler,Makaía M Papasergi-Scott,
Nature structural & molecular biologypp.1-10, (2024)
John Janetzko, Rabindra Shivnaraine, Jonathan C. Deutsch, Yuqi Shi,Weijing Liu,Matthieu Masureel, Steven Chu,Rosa Viner,Brian K. Kobilka
ASPET 2024 Annual Meeting Abstract - Cellular and Molecular Pharmacology (2024)
Hossein Batebi,Guillermo Pérez‐Hernández, Jesper Mathiesen, Mingyu Shi, Johanna K. S. Tiemann, Ramón Guixà-González, Franziska Reinhardt, Peter F. Stadler, Patrick Scheerer,Brian K. Kobilka,Xiangyu Liu,Peter W. Hildebrand
Research Square (Research Square) (2023)
NATURE COMMUNICATIONSno. 1 (2023)
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