I am an expert computational chemist and molecular modeller. I am skilled in the determination of protein structure by X-ray crystallography, in the analysis of protein structure, and in the design of protein mimetics and small-molecule inhibitors of protein function. I have authored over 150 papers in peer-reviewed journals, 2 book chapters and 3 invited reviews. Here I studied the energetics and reactions of ionic species in the gas-phase, with particular emphasis in structural chemistry, thermochemistry, intermolecular processes and spectroscopy. Of particular note was my work on the accurate calculation of proton transfer reactions that led to many high-impact papers.