Development of single cell phosphoprotein analysis in myeloid leukemia patient for phenotype analysis of mutations in signalling pathways, explore phosphoprotein signaling response for prognostic information in cancer, as biomarkers for therapy guidance in clinical trials and in elucidation of key physiological responses. In collaboration with Dr. McCormack, establishment of animal models and advanced molecular imaging of myelogen leukemia for development of p53- and signalling-targeted therapy.