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职业迁徙
个人简介
We use microchip techniques for live cell imaging and screening to characterize immune response at the single cell level. T cell and natural killer (NK) cells have remarkable abilities to mediate targeted attack against virus-infected or malignant cells. In adoptive cell therapy these qualities are used to treat primary malignancies, life-threatening virus infections or leukemic relapses after allogeneic hematopoietic stem cell transplantation. Although this therapy has shown promising results we have only a remote understanding of how to utilize T and NK cells to their full potential. A major challenge is to select and prepare cells that mediate anti-tumor effects without causing life-threatening side effects such as graft versus host disease. By better understanding of how populations of NK cells and T cells are built up by individual cells with varying capacity to respond to stimuli we will be able to improve current methods for immunotherapy.
研究兴趣
论文共 147 篇作者统计合作学者相似作者
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Luca A Andronico, Yidan Jiang,Valentina Carannante, Sofiia Iskrak,Patrick A. Sandoz,Jaromir Mikes, Andrey S Klymchenko,Marcus Buggert,Anders Osterborg,Bjorn Onfelt,Petter Brodin,Erdinc Sezgin
biorxiv(2024)
Valentina Carannante,Niklas Sandstrom,Karl Olofsson,Shi Yong Neo,Patrick Albert Sandoz,Hanna Van Ooijen,Quentin Verron, Jacopo Fontana, Damien Toullec, Elisabeth Moussaud-Lamodiere,Brinton Seashore-Ludlow,Thomas Frisk,
CANCER RESEARCHno. 7 (2023)
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Research Square (Research Square) (2023)
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Chiara Zambarda,Karolin Guldevall, Damien Toullec, Susanne Wingert, Christian Breunig,Sheena Pinto, Jacopo Fontana, Joachim Koch,Bjorn Onfelt
CANCER RESEARCHno. 7 (2023)
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Cancer Researchno. 7_Supplement (2023): 2950-2950
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Blood advancesno. 16 (2023): 4492-4504
Methods in Cell Biology (2023): 195-208
Nature communicationsno. 1 (2023): 6035-16
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Frontiers in Immunology (2023)
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Quirin Hammer,Karlo Perica,Hanna van Ooijen,Rina Mbofung,Pouria Momayyezi, Erika Varady, Karen E Martin,Yijia Pan,Mark Jelcic,Brian Groff,Ramzey Abujarour,Silje Krokeide,
bioRxiv : the preprint server for biology (2023)
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