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My research program focuses on the structure and function of type IV collagen, the major constitutent of basement membranes (BMs). BMs are a specialized form of extracellular matrix that compartmentalizes tissues and play an important role in tissue remodeling and morphogenesis. BM function is impaired in both hereditary and acquired diseases that affect type IV collagen. In Alport syndrome, a hereditary renal disease, the collagen genes are mutated. In Goodpasture syndrome, a rapidly progressive renal disease with lung hemorrhage, the collagen is the target for autoantibodies. In diabetes, the vascular complications of nephropathy and retinopathy also appear to involve this collagen.
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Papers共 400 篇Author StatisticsCo-AuthorSimilar Experts
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bioRxiv : the preprint server for biology (2023)
Jacob A. Summers, Madison Yarbrough,Min Liu,W. Hayes Mcdonald,Billy G. Hudson,Jose C. Pastor-Pareja,Sergei P. Boudko
Sergei P. Boudko, Elizabeth H. Konopka, Woojin Kim,Yuki Taga,Kazunori Mizuno,Timothy A. Springer,Billy G. Hudson,Terence I. Moy,Fu-Yang Lin
JOURNAL OF BIOLOGICAL CHEMISTRYno. 7 (2023): 104901-104901
Biochemical and biophysical research communications (2023): 152-156
Biochemical and biophysical research communications (2023): 149237-149237
Elena N Pokidysheva, Neve Redhair, Octavia Ailsworth,Patrick Page-McCaw,Louise Rollins-Smith, Vijayishwer Singh Jamwal,Yuko Ohta,Hans Peter Bächinger,Prayag Murawala,Martin Flajnik,Agnes B Fogo,Dale Abrahamson,
Sergei P Boudko,Vadim K Pedchenko,Elena N Pokidysheva, Alena M Budko, Rachel Baugh, Patrick Toby Coates,Aaron L Fidler, Heather M Hudson,Sergey V Ivanov, Carl Luer, Tetyana Pedchenko, Robert L Preston,
The Journal of biological chemistryno. 11 (2023): 105318-105318
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