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Career Trajectory
Bio
Distinctions include the Pfizer Research Award (1997, jointly with Dr. P. Lötscher), the Prof. Dr. Max. Clöetta Price (2003) and the Royal Society-Wolfson Research Merit Award (2007). He is a member of many academic societies, including the Henry Kunkel Society. Research of Prof. Moser’s group centers on human chemokines and their receptors expressed by immune cells. Initial work focused on the identification of chemokine receptors (starting with the IL-8 receptors, CXCR1 and CXCR2), followed by their biochemical and functional characterization. His group was first in identifying the human chemokine receptors CXCR3, CXCR4, CXCR5, CXCR6, CCR3 and CCR8. These findings enabled them to investigate (i) the role of CXCR4 in HIV infection, (ii), chemokine receptor antagonists, (iii) control of T cell migration (discovery of follicular B helper T (TFH) cells), and (iv) role of homeostatic chemokines in tissue homeostasis and immune defence. Finally, his group identified gdT-APCs, human gdT cells with professional antigen presentation functions, and this discovery is now being translated into the clinics (cellular immunotherapy of cancer patients). Long-standing collaborators included Prof. C. Mackay (Monash University, Melbourne). Prof. F. Arenzana-Seisdedos (Pasteur Institute, Paris) and Prof. I. Clark-Lewis (UBC, Vancouver). Several of these findings led to patents, and Prof. Moser is frequently asked for advice by major pharmaceutical companies.
Research Interests
Papers共 292 篇Author StatisticsCo-AuthorSimilar Experts
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Christopher J Tyler,Inva Hoti, Daniel D Griffiths,Simone M Cuff, Robert Andrews, Maximilian Keisker,Raya Ahmed, Hinrich P Hansen,James O Lindsay,Andrew J Stagg,Bernhard Moser,Neil E McCarthy,
Discovery immunologyno. 1 (2024): kyae008-kyae008
Current opinion in neurologyno. 5 (2023): 416-423
Journal of the American College of Cardiologyno. 7 (2023): 653-664
medrxiv(2023)
Biologyno. 1475 (2022): 1475-1475
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