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职业迁徙
个人简介
My research interests in molecular systems biology and engineering protein post-translational modifications.
The research in my group focuses on the mechanisms, biological roles and applications in biotechnology of glycosylation, the most abundant and complex post-translational modification of proteins. Glycosylation is important in biological processes such as viral infection, cancer, and development. This is because glycosylation is essential in biological activities as diverse as protein folding, fine-tuning protein enzymatic activity and determining protein-protein interactions. Half of all proteins are glycosylated, and a single protein can be modified by hundreds of different sugar moieties.
The diversity of glycoproteins therefore requires that we take a systems biology approach in our research. All our projects use a core set of methods in molecular biology, genetic manipulation, protein biochemistry, protein analysis and mass spectrometry. We aim to understand the mechanisms controlling glycosylation in these various systems to develop diagnostics, therapies, vaccines and applications in biotechnology.
We also use our systems biology approaches in diverse national and international collaborations in biomedicine, infectious disease, agriculture, and beverages.
The research in my group focuses on the mechanisms, biological roles and applications in biotechnology of glycosylation, the most abundant and complex post-translational modification of proteins. Glycosylation is important in biological processes such as viral infection, cancer, and development. This is because glycosylation is essential in biological activities as diverse as protein folding, fine-tuning protein enzymatic activity and determining protein-protein interactions. Half of all proteins are glycosylated, and a single protein can be modified by hundreds of different sugar moieties.
The diversity of glycoproteins therefore requires that we take a systems biology approach in our research. All our projects use a core set of methods in molecular biology, genetic manipulation, protein biochemistry, protein analysis and mass spectrometry. We aim to understand the mechanisms controlling glycosylation in these various systems to develop diagnostics, therapies, vaccines and applications in biotechnology.
We also use our systems biology approaches in diverse national and international collaborations in biomedicine, infectious disease, agriculture, and beverages.
研究兴趣
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Jason N Busby, Sarah Trevelyan,Cassandra L Pegg,Edward D Kerr,Benjamin L Schulz,Irene Chassagnon,Michael J Landsberg, Mitchell K Weston,Mark R H Hurst,J Shaun Lott
IUCrJ (2024)
Jason N. Busby, Sarah Trevelyan,Cassandra L. Pegg,Edward D. Kerr,Benjamin L. Schulz,Irene Chassagnon,Michael J. Landsberg, Mitchell K. Weston,Mark R. H. Hurst,J. Shaun Lott
IUCrJno. 3 (2024)
Elena Hakme, Ida Kallehauge Nielsen, Jennifer Fermina Madsen, Lasse Munch Storkehave, Mette Skjold Elmelund Pedersen,Benjamin Luke Schulz,Mette Erecius Poulsen,Timothy John Hobley,Lene Duedahl-Olesen
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENTno. 1 (2024): 45-59
Miljan Stupar,Lendl Tan,Edward D. Kerr, Christopher J. De Voss,Brian M. Forde,Benjamin L. Schulz,Nicholas P. West
Nature Communicationsno. 1 (2024): 1-14
Kyle L, Macauslane,Cassandra L. Pegg,Amanda S. Nouwens,Edward D. Kerr, Joy Seitanidou,Benjamin L. Schulz
biorxiv(2024)
Ariel Isaacs,Yu Shang Low, Kyle L. Macauslane, Joy Seitanidou,Cassandra L. Pegg,Stacey T. M. Cheung,Benjamin Liang,Connor A. P. Scott,Michael J. Landsberg,Benjamin L. Schulz,Keith J. Chappell,Naphak Modhiran,
Nature Communicationsno. 1 (2023): 1-10
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