Department of Medical Biochemistry and Biophysics
Karolinska Institutet
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基本信息
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个人简介
My research interests were originally in cholesterol metabolism with emphasis on reaction mechanisms. After the structural work on prostaglandins with Sune Bergström in 1959-1962 I have mainly been interested in transformation products of arachidonic acid. This has led to the discovery of endoperoxides, thromboxanes and the leukotrienes, and my group has mainly been involved in studying the chemistry, biochemistry and biology of these compounds and their role in biological control system. The research has implications in several clinical areas, particularly in thrombosis, inflammation and allergy.