![https://static.aminer.cn/upload/avatar/253/694/1661/5617e31545ce1e5963ea25b4_1.png](https://avatarcdn.aminer.cn/upload/avatar/253/694/1661/5617e31545ce1e5963ea25b4_1.png!160)
Barry Marshall Lester
Professor
Center for the Study of Children At Risk
The Warren Alpert Medical School, Brown University;Department of Pediatrics, The Warren Alpert Medical School, Brown University;Department of Psychiatry and Human Behavior, The Warren Alpert Medical School, Brown University
Follow
Claim
分享
Follow
Claim
分享
基本信息
views: 1
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Our research, as well as the research of many others, has shown that biological insults can lead to poor developmental outcome in children at risk but that many of these effects can be attenuated or exacerbated by social and environmental factors. We study a broad range of typical and atypical developmental outcomes including neurodevelopmental, cognitive and academic deficits, temperament, social and emotional development, antisocial behavior, psychopathology, and substance use onset. Our group also studies different (but often overlapping) populations of children at biological and/or social risk. Examples of biological risk include prenatal exposures to legal and illegal substances of abuse, maternal depression, psychotropic medication, intrauterine growth retardation and stress; prematurity, fetal and newborn neurobehavioral deficits. Developmental outcomes are also mediated by physiological mechanisms, thus our work also includes the study of heart rate variability, respiratory activity, electrodermal responses and cortisol reactivity. Examples of social risk factors include poverty, the quality of the home environment, parenting, including mental status, changes in caregiving and other aspects of childhood adversity and environmental toxicity such as maltreatment. We also use cross-cultural designs to study "naturalistic" experiments in environmental and parenting conditions. The study of the interplay between biological and social factors provides an understanding of the mechanisms that determine developmental outcome. For example, one way in which the environment (prenatal or postnatal) alters behavior is through epigenetic mechanisms and this has become a major focus of our current research. The study of children at risk enables us to understand the unfolding of developmental processes that will lead to the development of preventive interventions to minimize or eradicate the forces that drive adverse outcome in children.
Research Interests
Papers共 392 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
NEW ENGLAND JOURNAL OF MEDICINEno. 12 (2024): 1069-1079
Pediatric Researchpp.1-9, (2024)
The American journal of clinical nutrition (2024)
Jennifer Check, Coral Shuster,Julie Hofheimer, Marie Camerota, Lynne M Dansereau,Lynne M Smith, Brian S Carter, Sheri A DellaGrotta, Jennifer Helderman, Howard Kilbride, Cynthia M Loncar,Elisabeth McGowan,
JAMA network openno. 7 (2024): e2420382-e2420382
DEVELOPMENTAL PSYCHOLOGY (2024)
The Journal of Pediatrics (2024): 114050-114050
Epigenomics (2024)
JAMA PEDIATRICSno. 2 (2024): 168-175
JAMA INTERNAL MEDICINEno. 3 (2024): 242-251
Pediatric Researchpp.1-8, (2024)
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn