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Dr. Schmidt’s research focuses on collaborative neonatal randomized trials that have clinically important, long-term outcomes such as growth and development. Examples of trials she directed in the past include the “Trial of Indomethacin Prophylaxis in Preterms.” In this study, 1,202 extremely low-birth-weight infants from five countries were followed to the end of the second year of life. The results from the study showed that the high rate of mental and motor deficits in these children is not improved by prophylactic treatment with indomethacin. She is also the principal investigator of the “Caffeine for Apnea of Prematurity” trial, which enrolled over 2,000 very low-birth-weight infants in North America, Europe, Israel and Australia. Caffeine has been used for more than 30 years to regulate the breathing of very preterm babies, but without sufficient knowledge of the possible benefits and risks. To date, this trial has shown that caffeine therapy for apnea of prematurity improves the rate of survival without neurodevelopmental disability up to two years after very preterm birth. This study will continue to follow the study participants well into school age.
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Guowei Li, Yingxin Liu, Jingyi Zhang,Sara B DeMauro,Qiong Meng,Lawrence Mbuagbaw,Barbara Schmidt,Haresh Kirpalani,Lehana Thabane
Pediatricsno. 3 (2024)
The Journal of pediatrics (2023): 113488-5
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The Journal of Pediatrics (2023): 113488-113488
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K.L. Watterberg,M.C. Walsh, L. Li,S. Chawla,C.T. D'Angio,R.N. Goldberg, S.R. Hintz,M.M. Laughon,B.A. Yoder,K.A. Kennedy,G.E. McDavid, C. Backstrom-Lacy,
Obstetric Anesthesia Digestno. 3 (2022): 139-140
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Erik A Jensen,Robin K Whyte,Barbara Schmidt,Dirk Bassler,Nestor E Vain,Robin S Roberts, Canadian Oxygen Trial Investigators
Updates on Neonatal Chronic Lung Diseasepp.245-256, (2020)
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