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个人简介
Dr. Bach was born in Vienna, Austria, in 1934, the younger of two sons of Leo Bach and Gertrude Rosenfeld. After Kristallnacht (the infamous "Night of Broken Glass" in 1938), he fled with his brother, Berthold, to England on the Kindertransport, where he was later reunited with his parents. An American soldier sponsored the Bach family's emigration to the United States, and they settled in Burlington, Vermont. Dr. Bach graduated from Harvard University, attended the Washington University School of Medicine in St. Louis, and received his MD from Harvard Medical School. He completed his internship and residency training at New York University, Bellevue Hospital, and a fellowship in genetics. In 1964 he described the mixed lymphocyte culture (MLC) reaction for the purpose of testing tissue compatibility between donors and recipients for organ and bone marrow transplantation. In 1965, Dr. Bach joined the faculty at the University of Wisconsin, Madison, where he spent the next 14 years. During his tenure there, he made several major scientific discoveries that over the ensuing decades resulted in countless lives being saved. In 1967, he led the team that performed the first successful matched bone marrow transplant on a patient at the same time that his colleague, Robert A. Good, MD, performed a similar procedure using the MLC in Minnesota. He described the human leukocyte antigen (HLA) Class II locus and its antigens, part of the major histocompatibility complex in humans, and characterized the immunobiology of other major histocompatibility antigens that play an important role in organ and bone marrow transplantation. Dr. Bach was on the faculty of the University of Minnesota, Minneapolis, from 1979-1992, where he continued pioneering studies in the immunogenetics of T cell immune responses. He was recruited to the New England Deaconess Hospital Department of Surgery in 1992 and became director of the Sandoz Center for Immunobiology. In 1995, he became a faculty member of newly merged Beth Israel Deaconess Medical Center and was appointed the Lewis Thomas Professor of Surgery at Harvard Medical School.
研究兴趣
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Marie Rose van Schravendijk, John E. Coligan,William E. Biddison, Ted H. Hansen,Richard A. Zeff,Gertrude M. Pfaffenbach,Stanley G. Nathenson,J. Scott Cairns,Fritz H. Bach
Paradoxes in Immunologypp.287-298, (2019)
Interleukin-2 and Killer Cells in Cancerpp.25-40, (2018)
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