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个人简介
The main focus of the current research in the Frølund group is on GHB/CaMK2 pharmacology and the ionotropic GABAA receptors but also covers nACh receptors and the GABA relevant transporters GAT and TauT. The overall goal is to develop molecular probes and novel methodologies to obtain insight into identity, localization, function and therapeutic potential of target receptors/transporters and to match orphan ligands and binding sites with neuroprotection in focus. The approaches comprise structure-activity studies, development of photoligands for determination of localization, mobility and activation of target proteins, and engineered molecular probes for ligand-protein crystallization, identification and probing of binding sites, bioorthogonal chemistry, targeted delivery and rewiring of cell signaling.
研究兴趣
论文共 169 篇作者统计合作学者相似作者
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biorxiv(2024)
Jonas Petersen,Mette Q Ludwig, Vaida Juozaityte,Pablo Ranea-Robles, Charlotte Svendsen,Eunsang Hwang, Amalie W Kristensen,Nicole Fadahunsi,Jens Lund, Alberte W Breum,Cecilie V Mathiesen, Luisa Sachs,
Natureno. 8014 (2024): 1133-1141
Medicinal Chemistry Researchno. 12 (2023): 2587-2587
Yongsong Tian,Mohamed Shehata, Stine Gauger, Carolina Veronesi,Louise Hamborg,Louise Thiesen,Jesper Bruus-Jensen,Johanne Schlieper Royssen,Ulrike Leurs, Anne Sofie Larsen,Jacob Krall,Sara Solbak,
crossref(2022)
Francesco Bavo, Heleen de-Jong,Jonas Petersen,Christina Birkedahl Falk-Petersen,Rebekka Löffler, Emma Sparrow,Frederik Rostrup,Jannik Nicklas Eliasen,Kristine S Wilhelmsen, Kasper Barslund,Christoffer Bundgaard,Birgitte Nielsen,
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作者统计
#Papers: 169
#Citation: 4187
H-Index: 34
G-Index: 34
Sociability: 6
Diversity: 3
Activity: 28
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